RHBDD2 and SNPH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHBDD2	SNPH
Description		rhomboid domain containing 2	syntaphilin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Cytoplasmic Microtubule Membrane Neuron Projection Synapse Presynapse
	Molecular Function	Serine-type Endopeptidase Activity Signal Recognition Particle Binding Protein Binding	Protein Binding Syntaxin-1 Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway	Neurotransmitter Secretion Synaptic Vesicle Docking Neuron Differentiation
Pathways
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)	Body mass index ( 28552196) Lean body mass ( 28552196) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		60 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NEDD4 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SLC71A3P SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30 YAP1	6 interacting genes: ATP6V1H PRKACA RHBDD2 STUB1 STX1A XPA
Entrez ID		57414	9751
HPRD ID		11492	16081
Ensembl ID		ENSG00000005486	ENSG00000101298
Uniprot IDs		Q6NTF9	A0A3B3IRY9 O15079
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Synaptic Transmission, Dopaminergic Mitochondrial Envelope Mitochondrion Organization Apoptotic Signaling Pathway Response To Amphetamine Dopamine Metabolic Process Response To Alkaloid Regulation Of Catecholamine Secretion Protein Binding Response To Amine Membrane Epithelial Cell Proliferation Mitochondrial Membrane Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway Mitochondrial Matrix Catecholamine Catabolic Process Catecholamine Metabolic Process Dopamine Catabolic Process Protein Localization To Mitochondrion	Regulation Of Autophagy Regulation Of Macroautophagy Cellular Response To Heat Response To Heat Proteasomal Protein Catabolic Process Myosin Head/neck Binding Nucleotide-excision Repair, DNA Damage Recognition Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Chaperone-mediated Protein Complex Assembly ERAD Pathway Regulation Of Hormone Levels Regulation Of Steroid Metabolic Process Kinase Binding Regulation Of System Process Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Cellular Response To Stress Intracellular Signal Transduction Response To Temperature Stimulus Regulation Of Insulin Secretion Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Proteolysis Involved In Protein Catabolic Process Protein Localization To Lipid Droplet Regulation Of Muscle Contraction Protein Catabolic Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Nucleotide-excision Repair Factor 1 Complex Negative Regulation Of Vascular Associated Smooth Muscle Contraction Ubiquitin Conjugating Enzyme Complex CAMP-dependent Protein Kinase Complex Regulation Of Hormone Secretion Regulation Of Peptide Hormone Secretion Cellular Response To Parathyroid Hormone Stimulus Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Glucagon Stimulus Regulation Of Blood Circulation Protein Domain Specific Binding CAMP-dependent Protein Kinase Activity Interleukin-2-mediated Signaling Pathway Regulation Of Muscle System Process Cellular Response To Epinephrine Stimulus High-density Lipoprotein Particle Assembly Cytoplasmic Vesicle Macromolecule Catabolic Process Mitochondrial Protein Catabolic Process Regulation Of Protein Secretion CAMP/PKA Signal Transduction Nucleotide-activated Protein Kinase Complex
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