NIPBL and HINFP

Number of citations of the paper that reports this interaction (PMID 17577209)
8

Data Source:
BioGRID (two hybrid)

		NIPBL	HINFP
Gene Name		Nipped-B homolog (Drosophila)	histone H4 transcription factor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm SMC Loading Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cajal Body
	Molecular Function	Chromatin Binding Protein Binding Protein C-terminus Binding Mediator Complex Binding Histone Deacetylase Binding Protein N-terminus Binding Chromo Shadow Domain Binding	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Enzyme Binding Histone Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Metanephros Development Heart Morphogenesis Outflow Tract Morphogenesis Cellular Response To DNA Damage Stimulus Mitotic Sister Chromatid Cohesion Brain Development Sensory Perception Of Sound Stem Cell Maintenance Positive Regulation Of Histone Deacetylation Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Protein Localization Embryonic Forelimb Morphogenesis Forelimb Morphogenesis External Genitalia Morphogenesis Positive Regulation Of Multicellular Organism Growth Ear Morphogenesis Regulation Of Hair Cycle Fat Cell Differentiation Positive Regulation Of Ossification Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Embryonic Development Embryonic Digestive Tract Morphogenesis Developmental Growth Eye Morphogenesis Regulation Of Developmental Growth Embryonic Viscerocranium Morphogenesis Cognition Face Morphogenesis Gall Bladder Development Uterus Morphogenesis Cellular Response To X-ray	DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle In Utero Embryonic Development DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Mitotic Telophase/Cytokinesis Cohesin Loading onto Chromatin Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: CBX3 CBX5 CDK6 DBN1 HINFP MAU2 PRSS23 SP100	25 interactors: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TRA2B TRAF2 TRIM44 TTF2 U2AF1 ZNHIT1
Entrez ID		25836	25988
HPRD ID		10560	07387
Ensembl ID		ENSG00000164190
Uniprot IDs		Q6KC79	Q9BQA5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cell Dedifferentiation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Fas Signaling Pathway Cell Communication By Chemical Coupling Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Maintenance Of Mitotic Sister Chromatid Cohesion Mitotic Cell Cycle Chromatin Remodeling Negative Regulation Of Protein Export From Nucleus Negative Regulation Of Cellular Senescence Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Chromosome Organization Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Hematopoietic Stem Cell Differentiation Cell Communication By Electrical Coupling Negative Regulation Of Cell Aging Mitotic Sister Chromatid Cohesion Dentate Gyrus Development Type B Pancreatic Cell Development Negative Regulation Of Viral Transcription Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Astrocyte Development Type B Pancreatic Cell Differentiation Cell Cycle Lateral Ventricle Development Enteroendocrine Cell Differentiation Cell Division	RNA Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process RNA Processing RNA Splicing Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Histone Deacetylation Termination Of RNA Polymerase II Transcription Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Protein Deacetylation RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone H4 Acetylation Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Pharynx Development DNA-templated Transcription, Termination Chromatin Modification Chromosome Organization Double-strand Break Repair Via Homologous Recombination Recombinational Repair External Genitalia Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Maintenance Of Mitotic Sister Chromatid Cohesion Uterus Morphogenesis Gall Bladder Development Negative Regulation Of G0 To G1 Transition Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Ossification Regulation Of RNA Biosynthetic Process Chromatin Organization Macromolecule Biosynthetic Process Histone Acetylation Cellular Response To X-ray MRNA Transport Internal Peptidyl-lysine Acetylation
Tagcloud ?		12q13 1p36 ankrd11 cdls cleaves cohesin cornelia deeper discriminating encompassing espl1 exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem novo partitioning rad21 recursive separase smc1a smc3 undetected	acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt2 wnt2b wnt5a wnt5b wnt7b
Tagcloud (Difference) ?		12q13 1p36 ankrd11 cdls cleaves cohesin cornelia deeper discriminating encompassing espl1 exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem novo partitioning rad21 recursive separase smc1a smc3 undetected	acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt2 wnt2b wnt5a wnt5b wnt7b
Tagcloud (Intersection) ?