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NIPBL and DBN1
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
HPRD
(two hybrid)
NIPBL
DBN1
Description
NIPBL cohesin loading factor
drebrin 1
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Chromosome
Cytosol
Integrator Complex
SMC Loading Complex
Extracellular Exosome
Scc2-Scc4 Cohesin Loading Complex
Cytoplasm
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Gap Junction
Cell Cortex
Postsynaptic Density
Actin Cytoskeleton
Membrane
Dendrite
Growth Cone
Cortical Cytoskeleton
Actomyosin
Cell Projection
Neuron Projection
Postsynaptic Membrane
Anchoring Junction
Cell Periphery
Glutamatergic Synapse
Postsynaptic Cytosol
Molecular Function
Chromatin Binding
Transcription Corepressor Activity
Protein Binding
Mediator Complex Binding
Histone Deacetylase Binding
Cohesin Loader Activity
Chromo Shadow Domain Binding
Promoter-specific Chromatin Binding
Actin Binding
Protein Binding
Profilin Binding
Cadherin Binding
Protein Sequestering Activity
Biological Process
Mitotic Sister Chromatid Segregation
Negative Regulation Of Transcription By RNA Polymerase II
Metanephros Development
Heart Morphogenesis
Outflow Tract Morphogenesis
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
DNA Damage Response
Mitotic Sister Chromatid Cohesion
Brain Development
Heart Development
Sensory Perception Of Sound
Intracellular Protein Localization
Regulation Of Gene Expression
Establishment Of Mitotic Sister Chromatid Cohesion
Maintenance Of Mitotic Sister Chromatid Cohesion
Somatic Stem Cell Population Maintenance
Embryonic Forelimb Morphogenesis
Forelimb Morphogenesis
External Genitalia Morphogenesis
Positive Regulation Of Multicellular Organism Growth
Ear Morphogenesis
Regulation Of Hair Cycle
Fat Cell Differentiation
Positive Regulation Of Ossification
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Embryonic Digestive Tract Morphogenesis
Embryonic Organ Morphogenesis
Digestive Tract Development
Developmental Growth
Eye Morphogenesis
Regulation Of Developmental Growth
Embryonic Cranial Skeleton Morphogenesis
Embryonic Viscerocranium Morphogenesis
Cognition
Face Morphogenesis
Gallbladder Development
Uterus Morphogenesis
Establishment Of Protein Localization To Chromatin
Cellular Response To X-ray
Chromatin Looping
Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Positive Regulation Of Neuron Migration
In Utero Embryonic Development
Actin Filament Organization
Nervous System Development
Cell Communication By Chemical Coupling
Cell Communication By Electrical Coupling
Cell Differentiation
Positive Regulation Of Synaptic Plasticity
Maintenance Of Protein Location In Cell
Regulation Of Neuronal Synaptic Plasticity
Generation Of Neurons
Regulation Of Dendrite Development
Positive Regulation Of Dendritic Spine Morphogenesis
Neural Precursor Cell Proliferation
Positive Regulation Of Receptor Localization To Synapse
Pathways
Cohesin Loading onto Chromatin
RHOD GTPase cycle
RHOH GTPase cycle
RHOBTB2 GTPase cycle
RHOBTB1 GTPase cycle
Drugs
Diseases
Cornelia de Lange syndrome (CdLS)
GWAS
Height (
25282103
28552196
31562340
)
Malaria (
31844061
)
Meat-related diet (
32066663
)
Obesity-related traits (
23251661
)
Weight (
28552196
)
Activated partial thromboplastin time (
22703881
)
Extremely high intelligence (
29520040
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
11 interacting genes:
CBX5
CDK6
DBN1
DSCR9
HINFP
MAP1LC3C
PCNA
PCNT
PRSS23
SP100
SUMO2
29 interacting genes:
ACD
BAK1
BTRC
CDK2AP2
DNMBP
DUSP23
ESR1
FHL1
HOMER2
MAP1LC3B
MAPK6
MEST
NIPBL
NUDT21
NUDT3
OGT
PFN1
POT1
PTEN
RABGAP1L
SNUPN
SUPT5H
TAB1
TERF1
TINF2
TPT1
UBE2D3
USP7
ZNF598
Entrez ID
25836
1627
HPRD ID
10560
00545
Ensembl ID
ENSG00000164190
ENSG00000113758
Uniprot IDs
A0A590UJS4
Q6KC79
Q16643
PDB IDs
6WG3
6WGE
7W1M
5Y1Z
5ZZ9
Enriched GO Terms of Interacting Partners
?
DNA Damage Response
Generation Of Neurons
PML Body
Negative Regulation Of Transcription By RNA Polymerase II
Cellular Response To Stress
Postsynaptic Cytosol
Chromosome, Telomeric Region
Cyclin-dependent Protein Kinase Holoenzyme Complex
Cyclin D2-CDK6 Complex
Maintenance Of Protein Location In Cell
PCNA Complex
Replisome
Negative Regulation Of DNA-templated Transcription
G1/S Transition Of Mitotic Cell Cycle
Cyclin D3-CDK6 Complex
Cyclin D1-CDK6 Complex
Negative Regulation Of RNA Biosynthetic Process
FBXO Family Protein Binding
Cell Communication By Chemical Coupling
Maintenance Of Protein Location
Maintenance Of Location In Cell
Maintenance Of Location
PCNA-p21 Complex
DNA Polymerase Processivity Factor Activity
Purine-specific Mismatch Base Pair DNA N-glycosylase Activity
Cell Cycle G1/S Phase Transition
Negative Regulation Of RNA Metabolic Process
Mitotic Telomere Maintenance Via Semi-conservative Replication
Dinucleotide Insertion Or Deletion Binding
Telomere Maintenance
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Neurogenesis
Positive Regulation Of Receptor Localization To Synapse
Positive Regulation Of Deoxyribonuclease Activity
Leading Strand Elongation
Regulation Of Fas Signaling Pathway
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of Establishment Of Protein Localization To Chromosome
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance
Organelle Organization
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomere Lengthening
Nucleoplasm
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Biosynthetic Process
RNA-templated DNA Biosynthetic Process
Negative Regulation Of Chromosome Organization
Nucleus
Regulation Of DNA Biosynthetic Process
Cellular Component Assembly
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Cellular Component Organization
Telomere Maintenance
DNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Chromosome Organization
Nuclear Body
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Chromosome Organization
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Cytoplasm
Cytosol
Rhythmic Process
Nucleic Acid Metabolic Process
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Telomeric D-loop Disassembly
Vagina Development
G-rich Strand Telomeric DNA Binding
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
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Tagcloud (Difference)
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Tagcloud (Intersection)
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