CRKL and RAPGEF1

  • Number of citations of the paper that reports this interaction (PMID 18835194)
  • 33
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

CRKL

RAPGEF1

Gene Name v-crk avian sarcoma virus CT10 oncogene homolog-like Rap guanine nucleotide exchange factor (GEF) 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 71 interactors: ABL1 AOX1 ARHGAP32 ARHGEF5 BCAR1 BCR BIK BLNK CBL CBLB CD34 CRK DAB1 DOCK2 DOK1 EPHB6 EPOR ERBB2 ERBB3 ETV6 EVL FCGR1A GAB1 GAB2 GAREM GRB2 GRN IFNAR1 IGF1R INPP5D INSR IRS4 ITGB1 KHDRBS1 KIDINS220 KIT LAMA5 LTBP4 LYN MAP4K1 MAP4K5 MEGF6 MSL1 NEDD9 NOTCH2 PDGFRA PHC2 PIK3R1 PIK3R2 PLEKHA1 PLSCR1 POLR1D PPFIBP2 PTPN11 PXN RAPGEF1 RPL31 SHANK3 SHC1 SOS1 SOS2 STAT5A STAT5B SYK TGFB1I1 TNS2 TYK2 WAC WAS WIPF1 YY1 16 interactors: ABL1 ATXN1 BCAR1 CRK CRKL GRB2 HCK HRAS MBIP NEDD9 RAP1B RHOQ RPS15 RRAS2 SHC1 SLC20A1
Entrez ID 1399 2889
HPRD ID 03596 02627
Ensembl ID ENSG00000099942 ENSG00000107263
Uniprot IDs P46109 Q13905 Q68DL3
PDB IDs 2BZX 2BZY 2DBK 2EO3 2LQN 2LQW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actions  adaptor  antiapoptotic  behavior  believed  chemotactic  converting  crkii  focused  grb2  igfs  implicated  intracellularly  ir  irs  mediates  metabolism  mitogenic  nucleus  occur  organogenesis  outlines  promoting  shc  signalling  signals  stimulating  substrate  transmitting 
abl  abrogated  c3g  catalytically  colocalized  crk  delineate  dephosphorylation  forskolin  golgi  guanine  imr  interacted  neurite  neuroblastoma  noncatalytic  outgrowth  pc3g  pervanadate  phospho  ptp  ptpn2  reorganization  src  substrate  tc  tc48  vanadate  y504 
Tagcloud (Difference) ?
actions  adaptor  antiapoptotic  behavior  believed  chemotactic  converting  crkii  focused  grb2  igfs  implicated  intracellularly  ir  irs  mediates  metabolism  mitogenic  nucleus  occur  organogenesis  outlines  promoting  shc  signalling  signals  stimulating  transmitting 
abl  abrogated  c3g  catalytically  colocalized  crk  delineate  dephosphorylation  forskolin  golgi  guanine  imr  interacted  neurite  neuroblastoma  noncatalytic  outgrowth  pc3g  pervanadate  phospho  ptp  ptpn2  reorganization  src  tc  tc48  vanadate  y504 
Tagcloud (Intersection) ?
substrate