FSHR and TOP1

  • Number of citations of the paper that reports this interaction (PMID 15196694)
  • 8
  • Data Source:
  • HPRD (two hybrid)

FSHR

TOP1

Gene Name follicle stimulating hormone receptor topoisomerase (DNA) I
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065)
  • Erectile dysfunction and prostate cancer treatment ( 20932654)
  • Polycystic ovary syndrome ( 22885925 21151128)
  • Radiation response ( 20923822)
Protein-Protein Interactions 20 interactors: ADRBK1 AKT2 APPL1 ARR3 CANX CBX5 FSHB GRK4 GRK6 RNR2 RPS27A S100A10 TOP1 TOP1MT TUG1 UBA52 UBB UBC YWHAQ ZBTB16 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I
Entrez ID 2492 7150
HPRD ID 00639 00535
Ensembl ID ENSG00000170820 ENSG00000198900
Uniprot IDs F5GZW2 P23945 P11387
PDB IDs 1XUN 1XWD 4AY9 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ancestral  arose  assigns  booroola  closely  deer  distance  divergence  duplication  fecb  fecundity  fshrs  gonadotrophin  lh  lhcgr  lhcgrs  linkage  mammalian  mammals  ovine  probes  recombinants  restriction  rise  sheep  today  tsh  tshr 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Difference) ?
ancestral  arose  assigns  booroola  closely  deer  distance  divergence  duplication  fecb  fecundity  fshrs  gonadotrophin  lh  lhcgr  lhcgrs  linkage  mammalian  mammals  ovine  probes  recombinants  restriction  rise  sheep  today  tsh  tshr 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Intersection) ?