BRD1 and FEZ2

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		BRD1	FEZ2
Gene Name		bromodomain containing 1	fasciculation and elongation protein zeta 2 (zygin II)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Zinc Ion Binding Histone Binding	Protein Binding
	Biological Process	Histone H3 Acetylation	Signal Transduction Nervous System Development Axon Guidance
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Natriuretic peptide levels ( 21273288) Schizophrenia ( 23894747)
Protein-Protein Interactions		9 interactors: FEZ1 FEZ2 H2AFX H3F3A HIST2H3C KIAA1377 SS18L1 VIM ZNF512B	18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251
Entrez ID		23774	9637
HPRD ID		06848	09213
Ensembl ID		ENSG00000100425	ENSG00000171055
Uniprot IDs		J3KNX6 O95696	Q9UHY8
PDB IDs		2KU3 2L43 2LQ6 3LYI 3RCW
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Chromatin Silencing DNA Methylation Regulation Of Neuron Projection Development Regulation Of Dendrite Morphogenesis Negative Regulation Of Gene Expression, Epigenetic DNA Modification Cell Projection Organization Regulation Of Cell Projection Organization Gene Silencing Regulation Of Dendrite Development Regulation Of Neuron Differentiation Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Generation Of Neurons Regulation Of Neurogenesis Chromatin Organization DNA Packaging Neurogenesis Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Bergmann Glial Cell Differentiation Neuron Projection Development Positive Regulation Of Neuron Projection Development Cell Development Heterocycle Metabolic Process Cell Projection Morphogenesis Cellular Aromatic Compound Metabolic Process Organelle Organization Regulation Of Cell Development Cell Part Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Component Organization Cellular Nitrogen Compound Metabolic Process Neuron Development DNA Conformation Change Positive Regulation Of Cell Projection Organization Gene Expression Negative Regulation Of Macroautophagy Chromosome Organization Regulation Of Metabolic Process Cell Morphogenesis DNA Metabolic Process Establishment Of Mitochondrion Localization Positive Regulation Of Neuron Differentiation	Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production
Tagcloud ?		acetylation acetyltransferase appearance causes cd4 cd8 chip confirms demonstrates dp dynamic enhancer enhancers h3k14 haematopoietic hat hbo1 indistinguishable insufficiency localizes machinery mark progenitors promotes responsible serves tcrbeta thymocytes variegated
Tagcloud (Difference) ?		acetylation acetyltransferase appearance causes cd4 cd8 chip confirms demonstrates dp dynamic enhancer enhancers h3k14 haematopoietic hat hbo1 indistinguishable insufficiency localizes machinery mark progenitors promotes responsible serves tcrbeta thymocytes variegated
Tagcloud (Intersection) ?