BRD1 and FEZ1

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BRD1	FEZ1
Gene Name		bromodomain containing 1	fasciculation and elongation protein zeta 1 (zygin I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite
	Molecular Function	Zinc Ion Binding Histone Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Histone H3 Acetylation	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Natriuretic peptide levels ( 21273288) Schizophrenia ( 23894747)	Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		9 interactors: FEZ1 FEZ2 H2AFX H3F3A HIST2H3C KIAA1377 SS18L1 VIM ZNF512B	57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		23774	9638
HPRD ID		06848	09212
Ensembl ID		ENSG00000100425	ENSG00000149557
Uniprot IDs		J3KNX6 O95696	Q99689
PDB IDs		2KU3 2L43 2LQ6 3LYI 3RCW
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Chromatin Silencing DNA Methylation Regulation Of Neuron Projection Development Regulation Of Dendrite Morphogenesis Negative Regulation Of Gene Expression, Epigenetic DNA Modification Cell Projection Organization Regulation Of Cell Projection Organization Gene Silencing Regulation Of Dendrite Development Regulation Of Neuron Differentiation Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Generation Of Neurons Regulation Of Neurogenesis Chromatin Organization DNA Packaging Neurogenesis Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Bergmann Glial Cell Differentiation Neuron Projection Development Positive Regulation Of Neuron Projection Development Cell Development Heterocycle Metabolic Process Cell Projection Morphogenesis Cellular Aromatic Compound Metabolic Process Organelle Organization Regulation Of Cell Development Cell Part Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Component Organization Cellular Nitrogen Compound Metabolic Process Neuron Development DNA Conformation Change Positive Regulation Of Cell Projection Organization Gene Expression Negative Regulation Of Macroautophagy Chromosome Organization Regulation Of Metabolic Process Cell Morphogenesis DNA Metabolic Process Establishment Of Mitochondrion Localization Positive Regulation Of Neuron Differentiation	Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated
Tagcloud ?		acetylation acetyltransferase appearance causes cd4 cd8 chip confirms demonstrates dp dynamic enhancer enhancers h3k14 haematopoietic hat hbo1 indistinguishable insufficiency localizes machinery mark progenitors promotes responsible serves tcrbeta thymocytes variegated	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Difference) ?		acetylation acetyltransferase appearance causes cd4 cd8 chip confirms demonstrates dp dynamic enhancer enhancers h3k14 haematopoietic hat hbo1 indistinguishable insufficiency localizes machinery mark progenitors promotes responsible serves tcrbeta thymocytes variegated	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Intersection) ?