LSM5 and LSM3

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (in vitro)

		LSM5	LSM3
Gene Name		LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol	Nucleus Cytosol Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Splicing, Via Spliceosome MRNA Processing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay	mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS		Palmitic acid (16:0) plasma levels ( 23362303)
Protein-Protein Interactions		11 interactors: EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 SMN1 SNRPE SNRPF	28 interactors: CEP95 CLNS1A DLX4 EEF1A1 GDF9 GSTA1 KEAP1 LSM1 LSM10 LSM2 LSM5 LSM6 LSM7 LSM8 SF3B2 SMN1 SNRPD1 SNRPD3 SNRPE SNRPG TCL1A THOC5 UTP14A WDR77 WDR83 XPC XRN2 YBX1
Entrez ID		23658	27258
HPRD ID		06285	06283
Ensembl ID		ENSG00000106355
Uniprot IDs		Q9Y4Y9	P62310
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Processing MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Spliceosomal SnRNP Assembly NcRNA Metabolic Process Catabolic Process Ribonucleoprotein Complex Assembly Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Spliceosomal Complex Assembly DNA-templated Transcription, Termination MRNA 3'-end Processing RNA 3'-end Processing RRNA Processing RRNA Metabolic Process Metabolic Process Cellular Macromolecular Complex Assembly Circadian Regulation Of Translation Ribosome Biogenesis Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA DNA Deamination Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Regulation Of MRNA Stability Regulation Of RNA Stability	MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone MRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Ribonucleoprotein Complex Assembly NcRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA-templated Transcription, Termination RNA Catabolic Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Aromatic Compound Catabolic Process Nuclear-transcribed MRNA Catabolic Process Spliceosomal Complex Assembly MRNA Catabolic Process MRNA 3'-end Processing Cellular Macromolecule Catabolic Process Cellular Macromolecular Complex Assembly RNA 3'-end Processing Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Catabolic Process Maturation Of SSU-rRNA Transcription, DNA-templated RNA Biosynthetic Process Ribosomal Small Subunit Biogenesis Oocyte Growth Nucleotide-excision Repair, DNA Damage Recognition Cellular Component Assembly Regulation Of Stem Cell Division Negative Regulation Of DNA Damage Checkpoint Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Progesterone Secretion Proteasomal Ubiquitin-independent Protein Catabolic Process CRD-mediated MRNA Stabilization
Tagcloud ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Difference) ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Intersection) ?