LSM5 and SNRPE

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		LSM5	SNRPE
Gene Name		LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	small nuclear ribonucleoprotein polypeptide E
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Vesicular Exosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process Hair Cycle
Pathways		mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Palmitic acid (16:0) plasma levels ( 23362303)
Protein-Protein Interactions		11 interactors: EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 SMN1 SNRPE SNRPF	19 interactors: CLNS1A DDX20 GEMIN5 GEMIN6 GEMIN7 HRAS IL7R LSM2 LSM3 LSM4 LSM5 SMN1 SMN2 SNRPD3 SNRPF SNRPG STRAP WDR77 YWHAQ
Entrez ID		23658	6635
HPRD ID		06285	00548
Ensembl ID		ENSG00000106355
Uniprot IDs		Q9Y4Y9	P62304
PDB IDs			1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Splicing MRNA Processing RNA Splicing, Via Transesterification Reactions Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Processing MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Aromatic Compound Catabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone MRNA Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Spliceosomal SnRNP Assembly NcRNA Metabolic Process Catabolic Process Ribonucleoprotein Complex Assembly Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Spliceosomal Complex Assembly DNA-templated Transcription, Termination MRNA 3'-end Processing RNA 3'-end Processing RRNA Processing RRNA Metabolic Process Metabolic Process Cellular Macromolecular Complex Assembly Circadian Regulation Of Translation Ribosome Biogenesis Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA DNA Deamination Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Regulation Of MRNA Stability Regulation Of RNA Stability	Spliceosomal SnRNP Assembly RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly NcRNA Metabolic Process RNA Metabolic Process Gene Expression Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Spliceosomal Complex Assembly Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process DNA-templated Transcription, Termination Cellular Metabolic Process MRNA 3'-end Processing RNA 3'-end Processing Aromatic Compound Catabolic Process Regulation Of Epithelial Cell Proliferation Interleukin-7-mediated Signaling Pathway Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Process Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of T Cell Mediated Cytotoxicity Cellular Macromolecule Catabolic Process Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Ruffle Assembly
Tagcloud ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Difference) ?		angles arrange assemble building heptameric heteroheptameric hexameric incorporate lsm1 lsm2 lsm23 lsm57 lsm6 lsm657 lsm7 monomers nonetheless plastic pockets preferences pull ring sme smf smg solved spliceosomal
Tagcloud (Intersection) ?