ZNF593 and GPR3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		ZNF593	GPR3
Description		zinc finger protein 593	G protein-coupled receptor 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Ribonucleoprotein Complex Binding Metal Ion Binding Preribosome Binding	G Protein-coupled Receptor Activity Protein Binding Sphingosine-1-phosphate Receptor Activity
	Biological Process	Ribosome Biogenesis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding	Sphingosine-1-phosphate Receptor Signaling Pathway Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Meiotic Nuclear Division Positive Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: DDIT4L GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 PICK1 POLR1H RAB1A SRPK2	3 interacting genes: GNPAT RXYLT1 ZNF593
Entrez ID		51042	2827
HPRD ID		15866	02587
Ensembl ID		ENSG00000142684	ENSG00000181773
Uniprot IDs		O00488	F1DAM5 P46089
PDB IDs		1ZR9 6LSS 6LU8 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8IDT 8IDY 8IE3 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR3 8RL2	8U8F 8WW2 8X2K
Enriched GO Terms of Interacting Partners?		JNK Cascade Phosphorylation Protein Phosphorylation P38MAPK Cascade Stress-activated MAPK Cascade MAP Kinase Kinase Kinase Activity Stress-activated Protein Kinase Signaling Cascade Magnesium Ion Binding Regulation Of Stress-activated Protein Kinase Signaling Cascade Protein Kinase Activator Activity MAPK Cascade Positive Regulation Of Mitotic DNA Damage Checkpoint Mannosyltransferase Complex Defense Response Phosphate-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Protein Serine Kinase Activity Alpha-1,6-mannosyltransferase Activity Intracellular Signaling Cassette Protein Serine/threonine Kinase Activity Negative Regulation Of Signaling I-kappaB Phosphorylation Linear Polyubiquitin Binding Negative Regulation Of Cell Communication Termination Of RNA Polymerase I Transcription Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress GPI Mannosyltransferase Activity	Glycerone-phosphate O-acyltransferase Activity Ribitol Beta-1,4-xylosyltransferase Activity Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Transcription Regulatory Region DNA Binding Cerebellum Morphogenesis Paranodal Junction Assembly Preribosome Binding Ether Lipid Biosynthetic Process Protein O-linked Glycosylation Via Mannose Negative Regulation Of DNA Binding Regulation Of Transcription Regulatory Region DNA Binding Ether Lipid Metabolic Process O-acyltransferase Activity Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Ribonucleoprotein Complex Binding Regulation Of DNA Binding Peroxisomal Matrix
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