PPP1R13B and CEP63

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		PPP1R13B	CEP63
Gene Name		protein phosphatase 1, regulatory subunit 13B	centrosomal protein 63kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Plasma Membrane	Spindle Pole Centrosome Centriole Cytosol
	Molecular Function	Protein Binding Transcription Factor Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Height ( 18391952)
Protein-Protein Interactions		15 interactors: APC BRCA1 CCDC184 CDC5L CEP63 KHDRBS1 MIPOL1 PLEKHA5 PPP1CA PPP1CC TNIK TP63 TP73 TRAF1 UBC	44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10
Entrez ID		23368	80254
HPRD ID		07345	07826
Ensembl ID		ENSG00000088808	ENSG00000182923
Uniprot IDs		Q96KQ4	Q96MT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage Cell Cycle Checkpoint Cell Cycle DNA Damage Checkpoint Negative Regulation Of Cell Cycle Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To DNA Damage Stimulus Regulation Of Signal Transduction Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Signal Transduction Regulation Of Cell Cycle Cellular Response To Stress Regulation Of Signaling Signaling Signal Transduction By P53 Class Mediator Cell Communication Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Positive Regulation Of Signal Transduction Cell Division Cellular Response To Stimulus Response To Radiation Regulation Of Apoptotic Process Glycogen Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Death Apoptotic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Programmed Cell Death Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Death Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Polysaccharide Metabolic Process Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Positive Regulation Of Cell Death Mitotic DNA Damage Checkpoint	Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process
Tagcloud ?		acetylase acinic biomarkers cdkn2a damaging define deletions describe efforts ep300 exome future gland induces insights landscape malignancies massive mutational necessary nonsynonymous noted parotid presentation provides salivary sequencing underpinnings underwent
Tagcloud (Difference) ?		acetylase acinic biomarkers cdkn2a damaging define deletions describe efforts ep300 exome future gland induces insights landscape malignancies massive mutational necessary nonsynonymous noted parotid presentation provides salivary sequencing underpinnings underwent
Tagcloud (Intersection) ?