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TSPYL4 and NINL
Number of citations of the paper that reports this interaction (PubMedID
26485645
)
58
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
HPRD
(two hybrid)
TSPYL4
NINL
Description
TSPY like 4
ninein like
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Microtubule
Molecular Function
Chromatin Binding
Protein Binding
Histone Binding
Calcium Ion Binding
Protein Binding
Metal Ion Binding
Biological Process
Nucleosome Assembly
Microtubule Anchoring At Centrosome
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Fast beta electroencephalogram (
28040410
)
Gemcitabine-induced early high-grade neutropenia in pancreatic cancer (
30889042
)
Metabolite levels (
23823483
)
Refractive error (
32231278
)
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Interacting Genes
14 interacting genes:
CCDC85B
CDK5RAP3
CELSR3
CEP57
GOLGA6L9
MAGEA4
NAP1L3
NINL
PNMA1
TFIP11
TH
TRIM38
ZNF655
ZRANB1
52 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSC1
TSPYL4
UTP14A
YJU2B
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
Entrez ID
23270
22981
HPRD ID
18236
11120
Ensembl ID
ENSG00000187189
ENSG00000101004
Uniprot IDs
Q9UJ04
Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Mitotic Spindle Pole
Nucleus
Protein Binding
Chromosome, Centromeric Region
Positive Regulation Of Mitotic Sister Chromatid Segregation
Spindle Pole
Regulation Of Metaphase Plate Congression
Kinetochore
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Histone Acetyltransferase Complex
Positive Regulation Of Chromosome Segregation
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Attachment Of Spindle Microtubules To Kinetochore
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Histone H4K16 Acetyltransferase Activity
Spindle Microtubule
Protein Localization To Chromosome
Regulation Of Sister Chromatid Segregation
Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Regulation Of RNA Metabolic Process
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle
Cytoskeleton
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Spindle Midzone Assembly
Histone H4 Acetyltransferase Activity
Peptidyl-lysine Acetylation
Negative Regulation Of Cell Cycle Phase Transition
Zinc Ion Binding
Regulation Of Chromosome Segregation
Regulation Of Mitotic Sister Chromatid Separation
RNA Splicing
Centrosome
Tagcloud
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Tagcloud (Difference)
?
Tagcloud (Intersection)
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