TSPYL4 and CELSR3

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		TSPYL4	CELSR3
Description		TSPY like 4	cadherin EGF LAG seven-pass G-type receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Plasma Membrane Adherens Junction Membrane
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Nucleosome Assembly	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Axonogenesis Dopaminergic Neuron Axon Guidance Serotonergic Neuron Axon Guidance Cell-cell Adhesion Mediated By Cadherin Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways
Drugs
Diseases
GWAS		Fast beta electroencephalogram ( 28040410) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Metabolite levels ( 23823483) Refractive error ( 32231278)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mental health study participation (provided email address) ( 31263887) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: CCDC85B CDK5RAP3 CELSR3 CEP57 GOLGA6L9 MAGEA4 NAP1L3 NINL PNMA1 TFIP11 TH TRIM38 ZNF655 ZRANB1	14 interacting genes: CLK1 CLUH DSCR9 DST IFT140 REST SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA
Entrez ID		23270	1951
HPRD ID		18236	09179
Ensembl ID		ENSG00000187189	ENSG00000008300
Uniprot IDs		Q9UJ04	Q9NYQ7
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Actin Filament Depolymerization Regulation Of Actin Filament Depolymerization Spectrin Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein-containing Complex Disassembly Actin Binding Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Actin Filament Capping Cell Cortex Cell Junction Organization Negative Regulation Of Dense Core Granule Biogenesis Negative Regulation Of Amniotic Stem Cell Differentiation Negative Regulation Of Actin Filament Polymerization Structural Constituent Of Synapse Postsynaptic Spectrin-associated Cytoskeleton Cytoskeleton Cortical Actin Cytoskeleton H Zone Negative Regulation Of Mesenchymal Stem Cell Differentiation Synapse Organization Regulation Of Cellular Component Size Regulation Of Actin Filament Organization Cerebellar Purkinje Cell Layer Morphogenesis Structural Constituent Of Postsynapse Heterochromatin Boundary Formation Negative Regulation Of Cell-cell Adhesion Mediated By Integrin Chromatin Remodeling
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