CYFIP1 and GAS7

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		CYFIP1	GAS7
Gene Name		cytoplasmic FMR1 interacting protein 1	growth arrest-specific 7
Image
Gene Ontology Annotations	Cellular Component	Ruffle MRNA Cap Binding Complex Focal Adhesion Lamellipodium SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Ruffle Cytoplasm Actin Filament
	Molecular Function	Protein Binding Protein Complex Binding Rac GTPase Binding Actin Filament Binding	Sequence-specific DNA Binding Transcription Factor Activity Actin Filament Binding
	Biological Process	Regulation Of Cell Shape Rac Protein Signal Transduction Lamellipodium Assembly Ruffle Organization Axon Extension Cognition Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Regulation Of Transcription, DNA-templated Cell Cycle Arrest Regulation Of Cell Shape Actin Filament Polymerization Neuron Projection Morphogenesis Actin Filament Bundle Assembly
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Intraocular pressure ( 22570627)
Protein-Protein Interactions		15 interactors: ACTA1 APBB1 EFHC2 EFTUD2 FMR1 FXR2 GAS7 GNB1 MEOX1 PPP1CC PRPF40A RAC1 RFX6 SCTR TCERG1	22 interactors: ABI1 ACTA1 APBB1IP ATXN1L CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH HNRNPU KHDRBS1 NCKAP1 NCKAP1L PACSIN1 RPLP0 SF1 SF3A1 SFPQ WAS WASF2 WDYHV1
Entrez ID		23191	8522
HPRD ID		05890	16011
Ensembl ID		ENSG00000068793	ENSG00000007237
Uniprot IDs		Q7L576	B7Z1Q2 O60861
PDB IDs		3P8C	2LX7 2YSH
Enriched GO Terms of Interacting Partners?		Response To Abiotic Stimulus Actin Filament Polymerization Pancreatic Epsilon Cell Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Pancreatic D Cell Differentiation Actin Filament Organization Response To Light Stimulus System Development Actin Polymerization Or Depolymerization Negative Regulation Of Translation Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Skeletal Muscle Fiber Adaptation Protein Polymerization Engulfment Of Apoptotic Cell Response To Radiation Tissue Development Multicellular Organismal Development Mast Cell Chemotaxis Sclerotome Development Regulation Of Cell Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Response To External Stimulus Energy Reserve Metabolic Process Cell Cycle Arrest Positive Regulation Of DNA Metabolic Process Cytoskeleton Organization Somite Specification	Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Lamellipodium Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Rac Protein Signal Transduction Regulation Of Arp2/3 Complex-mediated Actin Nucleation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Actin Nucleation Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Phagocytosis Fc Receptor Signaling Pathway Actin Filament Organization MRNA Metabolic Process Lamellipodium Morphogenesis MRNA 3'-splice Site Recognition Positive Regulation Of Immune System Process Lamellipodium Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Immune Response Endocytosis Cellular Component Assembly Actin Filament-based Movement Regulation Of Actin Filament-based Process Positive Regulation Of Cytoskeleton Organization Organelle Organization MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Actin Polymerization Or Depolymerization Innate Immune Response Regulation Of Cytoskeleton Organization Cellular Response To Stimulus Positive Regulation Of Lamellipodium Assembly Regulation Of Immune Response Megakaryocyte Development Regulation Of Immune System Process Positive Regulation Of Lamellipodium Organization RNA Processing Regulation Of Cellular Component Organization Vesicle-mediated Transport Megakaryocyte Differentiation Regulation Of Lamellipodium Assembly Movement Of Cell Or Subcellular Component
Tagcloud ?		4e bdnf boncat cap depends eif4e eif4g encoded find fmrp gtp implicate latter mek mnk1 mnks neurotransmission neurotrophic obscure overlap partner phosphorylates plasticity repressor silac subset synthesis translational whose	as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2
Tagcloud (Difference) ?		4e bdnf boncat cap depends eif4e eif4g encoded find fmrp gtp implicate latter mek mnk1 mnks neurotransmission neurotrophic obscure overlap partner phosphorylates plasticity repressor silac subset synthesis translational whose	as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc glaugen human660w interrogated kilobases lrp12 merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2
Tagcloud (Intersection) ?