CYFIP1 and EFHC2

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		CYFIP1	EFHC2
Gene Name		cytoplasmic FMR1 interacting protein 1	EF-hand domain (C-terminal) containing 2
Image
Gene Ontology Annotations	Cellular Component	Ruffle MRNA Cap Binding Complex Focal Adhesion Lamellipodium SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Complex Binding Rac GTPase Binding Actin Filament Binding	Calcium Ion Binding
	Biological Process	Regulation Of Cell Shape Rac Protein Signal Transduction Lamellipodium Assembly Ruffle Organization Axon Extension Cognition Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ACTA1 APBB1 EFHC2 EFTUD2 FMR1 FXR2 GAS7 GNB1 MEOX1 PPP1CC PRPF40A RAC1 RFX6 SCTR TCERG1	30 interactors: ARHGEF5 ARMC7 CCDC120 CCHCR1 CCNG2 CLIC3 COPE CYFIP1 DGCR6 EDC3 EGLN3 EMD EXOC8 JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 PBLD PLOD3 PTK6 RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		23191	80258
HPRD ID		05890	06540
Ensembl ID		ENSG00000068793
Uniprot IDs		Q7L576	Q5JST6
PDB IDs		3P8C	2Z13 2Z14
Enriched GO Terms of Interacting Partners?		Response To Abiotic Stimulus Actin Filament Polymerization Pancreatic Epsilon Cell Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Pancreatic D Cell Differentiation Actin Filament Organization Response To Light Stimulus System Development Actin Polymerization Or Depolymerization Negative Regulation Of Translation Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Skeletal Muscle Fiber Adaptation Protein Polymerization Engulfment Of Apoptotic Cell Response To Radiation Tissue Development Multicellular Organismal Development Mast Cell Chemotaxis Sclerotome Development Regulation Of Cell Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Response To External Stimulus Energy Reserve Metabolic Process Cell Cycle Arrest Positive Regulation Of DNA Metabolic Process Cytoskeleton Organization Somite Specification	Regulation Of Podosome Assembly
Tagcloud ?		4e bdnf boncat cap depends eif4e eif4g encoded find fmrp gtp implicate latter mek mnk1 mnks neurotransmission neurotrophic obscure overlap partner phosphorylates plasticity repressor silac subset synthesis translational whose
Tagcloud (Difference) ?		4e bdnf boncat cap depends eif4e eif4g encoded find fmrp gtp implicate latter mek mnk1 mnks neurotransmission neurotrophic obscure overlap partner phosphorylates plasticity repressor silac subset synthesis translational whose
Tagcloud (Intersection) ?