ATG2A and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 35044719)
104

Data Source:
BioGRID (unspecified method)

		ATG2A	MAP1LC3A
Description		autophagy related 2A	microtubule associated protein 1 light chain 3 alpha
Image
GO Annotations	Cellular Component	Phagophore Assembly Site Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Membrane Phagophore Assembly Site Membrane Organelle Membrane Contact Site Phagophore	Autophagosome Membrane Cytoplasm Late Endosome Autophagosome Cytosol Cytoskeleton Microtubule Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Autolysosome Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Protein-membrane Adaptor Activity Lipid Transfer Activity	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Pexophagy Lipid Transport Autophagy Positive Regulation Of Autophagy Piecemeal Microautophagy Of The Nucleus Reticulophagy Glycophagy Intermembrane Lipid Transfer Positive Regulation Of Autophagosome Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation JNK Cascade Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Response To Nutrient Levels Cellular Response To Amino Acid Starvation P38MAPK Cascade SMAD Protein Signal Transduction Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Cellular Response To Oxygen-glucose Deprivation Autophagosome Maturation
Pathways			Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245)	Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		3 interacting genes: CPEB2 MAP1LC3A MEOX2	100 interacting genes: ABTB3 AKAP13 AMBRA1 ANK2 ANK3 ANKRD62 AP5B1 APOBR APP APPL1 ARHGAP6 ATF7IP2 ATG13 ATG2A ATG4B ATG7 ATXN3 BCL9 BNIP3L BRD9 CAMSAP1 CARS2 CCPG1 CDC37 CSAG1 DPPA4 DVL2 EPHA7 FUNDC1 GPSM1 HTATSF1 IRGQ IRS4 KIF15 KXD1 LINC00696 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG MRTFA MTX1 MYBPC1 NBR1 NCOR1 NEDD4 NEDD4L NEK9 NEURL4 OPRM1 OPTN PCNT PHB1 PIAS4 PRPF40A RABGAP1 RABGAP1L RASAL3 RDH12 RELB RESF1 RETREG3 RIC1 RTKN RTN3 SEC62 SLA2 SP1 SP3 SRPK1 STBD1 STK10 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TMEM132C TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM25 TRIM32 TTN TUBA4A VPS9D1 ZBTB48 ZKSCAN4 ZNF304
Entrez ID		23130	84557
HPRD ID		17186	03144
Ensembl ID		ENSG00000110046	ENSG00000101460
Uniprot IDs		Q2TAZ0	Q9H492
PDB IDs		6KLR 8KBX 8KBY 8KC3 8SBK 8SBL 8Y1L	3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE 7R9W 7R9Z 7RA0 8T2L 8T35 8T36 8T4T
Enriched GO Terms of Interacting Partners?		Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Negative Regulation Of Cytoplasmic Translational Elongation Somite Specification Cellular Response To Oxygen-glucose Deprivation Response To Decreased Oxygen Levels Negative Regulation Of Translational Elongation Response To Iron(II) Ion Response To Oxygen Levels Response To Oxygen-glucose Deprivation Autolysosome Cellular Response To Nitrogen Starvation GTPase Inhibitor Activity Negative Regulation Of Cytoplasmic Translation Regulation Of Translational Elongation Segment Specification Somite Development Phosphatidylethanolamine Binding MRNA Regulatory Element Binding Translation Repressor Activity Ribosomal Large Subunit Binding Translation Regulator Activity Response To Lead Ion Ribosomal Small Subunit Binding Translation Factor Activity, RNA Binding Cellular Response To Copper Ion SMAD Protein Signal Transduction P38MAPK Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis MRNA 3'-UTR AU-rich Region Binding Response To Iron Ion Response To Copper Ion Regulation Of Cytoplasmic Translation Cellular Response To Oxygen-containing Compound Organelle Membrane Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Autophagosome Membrane Autophagosome Maturation Synapse Mitophagy Embryonic Pattern Specification JNK Cascade Skeletal Muscle Tissue Development Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Cellular Response To Hydrogen Peroxide Negative Regulation Of Endothelial Cell Migration Autophagy Of Mitochondrion Ribosome Binding	Autophagosome GTPase Activator Activity Regulation Of Cilium Assembly Autophagy Macroautophagy Positive Regulation Of Catabolic Process Positive Regulation Of Autophagy Regulation Of Organelle Assembly Autophagosome Assembly Regulation Of Cell Projection Organization Autophagosome Organization Regulation Of Cell Projection Assembly Cytoplasmic Vesicle Regulation Of Autophagy Regulation Of Plasma Membrane Bounded Cell Projection Organization Autophagy Of Mitochondrion Organelle Organization Cytosol Vacuole Organization Mitophagy Positive Regulation Of Macroautophagy Regulation Of Macroautophagy Regulation Of Cellular Component Organization Piecemeal Microautophagy Of The Nucleus Regulation Of Organelle Organization Microautophagy Nucleophagy Positive Regulation Of Metabolic Process Substrate Localization To Autophagosome M Band Cytoskeleton Organization Phagophore Assembly Site Vesicle-mediated Transport Transcription Repressor Complex Intracellular Protein Localization Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Microtubule Associated Complex Regulation Of Protein Localization Negative Regulation Of Viral Process Catabolic Process Protein Kinase Regulator Activity Suppression Of Viral Release By Host Regulation Of Viral Process Regulation Of GTPase Activity Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Catabolic Process Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity
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