SPG20 and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 15231748)
  • 65
  • Data Source:
  • HPRD (two hybrid)

SPG20

SMURF2

Gene Name spastic paraplegia 20 (Troyer syndrome) SMAD specific E3 ubiquitin protein ligase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 9 interactors: APP EPS15 ITCH PLIN3 SMURF1 SMURF2 TUBA1A WWP2 ZFYVE9 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 23111 64750
HPRD ID 06170 06901
Ensembl ID ENSG00000133104
Uniprot IDs Q8N0X7 Q96DE7 Q9HAU4
PDB IDs 2DL1 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenocarcinoma  arid1a  cdkn2a  contributor  contributors  dinucleotides  dock2  eac  elmo1  esophageal  exome  greatly  identifies  modifying  mutated  mutational  pairs  pik3ca  rac1  risen  sequencing  signature  smad4  spectra  subjected  tlr4  transversions  tumorigenesis  whole 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
adenocarcinoma  arid1a  cdkn2a  contributor  contributors  dinucleotides  dock2  eac  elmo1  esophageal  exome  greatly  identifies  modifying  mutated  mutational  pairs  pik3ca  rac1  risen  sequencing  signature  smad4  spectra  subjected  tlr4  transversions  tumorigenesis  whole 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?