SORL1 and PPP1CA

  • Number of citations of the paper that reports this interaction (PMID 22321011)
  • 2
  • Data Source:
  • BioGRID (two hybrid)

SORL1

PPP1CA

Gene Name sortilin-related receptor, L(DLR class) A repeats containing protein phosphatase 1, catalytic subunit, alpha isozyme
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 23565137)
  • Cardiovascular disease risk factors ( 20838585)
Protein-Protein Interactions 5 interactors: FURIN GGA1 GGA2 LRPAP1 PPP1CA 148 interactors: AATK AKAP1 AKAP11 AKAP9 AKT1 APAF1 AURKA BAD BAX BCL2 BCL2L1 BCL2L2 BRCA1 BTBD10 C1QA CAD CASC5 CAV1 CCDC181 CD2BP2 CDC5L CDH1 CEP170 CKB CLCN2 CLTC CNP CNST CNTN1 CREB1 CRK CSNK1E CSRNP1 CSRNP2 CUL1 CXXC1 DCTN1 DCX DEAF1 EED EIF2AK2 FRMPD4 FXYD1 GLIPR1L2 GLTSCR2 GPKOW H2AFX HEYL HSPA4 IBTK ID2 JPH3 KANK1 KCNQ1 KCTD20 KIAA1377 KIF13A KIF18A LMTK2 LPIN2 MAFG MAL2 MAP4K4 MAPK1 MAPK3 MIIP MPHOSPH10 MST1R MYO16 NCAM1 NDP NEK2 NOC2L NOM1 NONO PCDH7 PCNA PHACTR1 PHACTR3 PHACTR4 PHC1 PIAS1 PIAS3 PLCL2 POLR2A PPP1R10 PPP1R11 PPP1R13B PPP1R13L PPP1R15A PPP1R15B PPP1R16A PPP1R18 PPP1R1B PPP1R2 PPP1R26 PPP1R2P3 PPP1R2P9 PPP1R32 PPP1R37 PPP1R3B PPP1R3C PPP1R3D PPP1R3E PPP1R3G PPP1R8 PPP1R9A PPP1R9B PPP2CA PREX1 PRKCB PRKCD PRR16 PTEN RANBP9 RB1 RIF1 RPRD2 SFPQ SFRP1 SH3RF2 SKP1 SLC45A1 SNCAIP SORL1 SPRED1 STAM STAU1 SYTL2 TCTEX1D4 TOE1 TOR1AIP1 TOX4 TP53 TP53BP2 TPRN TUSC3 UBE2Z ULK1 VDR WBP11 WDR82 WWTR1 YLPM1 ZBTB11 ZFYVE16 ZFYVE9 ZNF827
Entrez ID 6653 5499
HPRD ID 03595 15942
Ensembl ID ENSG00000137642 ENSG00000172531
Uniprot IDs E9PP43 Q92673 P62136
PDB IDs 2DM4 3G2S 3G2T 3E7A 3E7B 3EGG 3EGH 3HVQ 3N5U 3V4Y 4G9J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  psen2  snps  sporadic  triggers  turn  unlikely 
0x  1x  adamts13  aspm  atp6v0a2  bioinformatic  bl  chickens  col12a1  fowl  grm5  interpretations  jungle  lrp2  obscn  plau  prkdc  resequencing  rnf168  sanger  sl  slv  smyth  stab2  ubc  ubiquitinylation  vitiliginous  vitiligo  xirp1 
Tagcloud (Difference) ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  psen2  snps  sporadic  triggers  turn  unlikely 
0x  1x  adamts13  aspm  atp6v0a2  bioinformatic  bl  chickens  col12a1  fowl  grm5  interpretations  jungle  lrp2  obscn  plau  prkdc  resequencing  rnf168  sanger  sl  slv  smyth  stab2  ubc  ubiquitinylation  vitiliginous  vitiligo  xirp1 
Tagcloud (Intersection) ?