SORL1 and GGA1

  • Number of citations of the paper that reports this interaction (PMID 11821067)
  • 25
  • Data Source:
  • HPRD (in vitro, in vivo, two hybrid)

SORL1

GGA1

Gene Name sortilin-related receptor, L(DLR class) A repeats containing golgi-associated, gamma adaptin ear containing, ARF binding protein 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 23565137)
  • Cardiovascular disease risk factors ( 20838585)
Protein-Protein Interactions 5 interactors: FURIN GGA1 GGA2 LRPAP1 PPP1CA 36 interactors: AFTPH AP1AR APP ARF1 ARF3 ARF5 ARF6 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB F8 GGA2 GGA3 IGF2R LRP3 M6PR RAB5A RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TSG101 UBC VPS18
Entrez ID 6653 26088
HPRD ID 03595 12078
Ensembl ID ENSG00000137642 ENSG00000100083
Uniprot IDs E9PP43 Q92673 Q6IC75 Q9UJY5
PDB IDs 2DM4 3G2S 3G2T 1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  psen2  snps  sporadic  triggers  turn  unlikely 
adpkd  arl3  autosomal  cilia  ciliary  ciliopathies  cleaved  couples  golgi  gps  localize  milieu  module  must  pc1  pc2  polycystic  polycystin  proper  proteolytically  rabep1  reach  sense  tgn  traffic  trafficking  transmembrane  tubular  whereby 
Tagcloud (Difference) ?
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  psen2  snps  sporadic  triggers  turn  unlikely 
adpkd  arl3  autosomal  cilia  ciliary  ciliopathies  cleaved  couples  golgi  gps  localize  milieu  module  must  pc1  pc2  polycystic  polycystin  proper  proteolytically  rabep1  reach  sense  tgn  traffic  trafficking  transmembrane  tubular  whereby 
Tagcloud (Intersection) ?