NCOA6 and RXRA

  • Number of citations of the paper that reports this interaction (PMID 10866662)
  • 36
  • Data Source:
  • HPRD (in vivo, two hybrid)

NCOA6

RXRA

Gene Name nuclear receptor coactivator 6 retinoid X receptor, alpha
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065)
  • Central corneal thickness ( 22814818 23493294)
  • Corneal structure ( 23291589)
  • Crohn's disease (need for surgery) ( 23665963)
  • Intelligence ( 22449649)
Protein-Protein Interactions 64 interactors: AR ASCC1 ATF2 BCL3 CD40 CEBPA CREBBP E2F1 EP300 ESR1 ESR2 FHOD1 FOS GHR GRIP1 GTF2A1 HIST2H3C HNF4A HSF1 JUN LAMTOR5 MED1 MED23 NCOA1 NCOR2 NFKB1 NR1H2 NR1H3 NR1H4 NR1I2 NR3C1 NUMA1 PARP1 PPARG PPARGC1A PRKDC PRMT2 RANBP9 RARA RB1 RBM14 RBM39 RELA RORB RORC RXRA RXRG SMAD2 SMAD3 SRC SRF TBP TGS1 THRA THRB TOP1 TRA TRB TXNRD2 UBC VDR XRCC5 XRCC6 ZNF335 113 interactors: ACVR1 ACVR1B ALOX15B ARID5A ARNTL BCL3 BRD8 CASP2 CHD9 CLOCK CNOT1 COPS2 CSNK2B CTCF CTNNB1 CTSL DNTTIP2 EDF1 ESR1 ESR2 FUS GADD45A GADD45G GATA2 GK GRIP1 GSK3B HDAC3 HDAC4 HMGA1 IGFBP3 ITGB3BP JAZF1 JMJD1C KIF1A MAPK1 MAPK3 MAPK7 MECR MED1 MED24 MED25 MPG MYOD1 NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NFKB1 NFKBIB NPAS2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR1I3 NR2E3 NR2F1 NR2F6 NR3C2 NR4A2 NRBF2 NRIP1 NSD1 PARP1 PLK1 PML POU2F1 POU2F2 PPARA PPARD PPARG PPARGC1A PRKD2 PRMT2 PSMC3IP PSMC5 RAD54L2 RARA RARB RARG RELA RNF8 ROBO4 RPS6KA6 SMAD2 SMARCD3 SMN1 SNW1 SP1 SRC SRF STAT1 TADA3 TAF11 TAF1B TBP TDG THRA THRB TK1 TMPRSS3 TRIM24 TRIP10 TRIP4 UBQLN4 VDR ZBTB16 ZNHIT3
Entrez ID 23054 6256
HPRD ID 05599 01577
Ensembl ID ENSG00000198646
Uniprot IDs F6M2K2 Q14686 F1D8Q5 P19793 Q6P3U7
PDB IDs 1BY4 1DSZ 1FBY 1FM6 1FM9 1G1U 1G5Y 1K74 1LBD 1MV9 1MVC 1MZN 1R0N 1RDT 1RXR 1XLS 1XV9 1XVP 1YNW 2ACL 2NLL 2P1T 2P1U 2P1V 2ZXZ 2ZY0 3DZU 3DZY 3E00 3E94 3FAL 3FC6 3FUG 3H0A 3KWY 3NSP 3NSQ 3OAP 3OZJ 3PCU 3R29 3R2A 3R5M 3UVV 4J5W 4J5X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
candidate  cardiomyopathy  coactivator  coding  contractile  dcm  defects  delta  depletion  dilated  dilation  dysfunction  embryonic  germline  heart  humans  idcm  idiopathic  left  lethality  malfunction  nonsynonymous  peroxisome  ppardelta  progressive  proliferator  sequencing  unclear  ventricular 
17q  22cm  canine  centromeric  cfa9  correspond  cosmid  cryba1  distal  dog  grp78  hsa17  hsa17q  hsa9q  hsa9q34  hspa5  lies  linkage  loci  map  mmu2  nf1  occupy  painting  places  probable  syntenic  telomeric  thirds 
Tagcloud (Difference) ?
candidate  cardiomyopathy  coactivator  coding  contractile  dcm  defects  delta  depletion  dilated  dilation  dysfunction  embryonic  germline  heart  humans  idcm  idiopathic  left  lethality  malfunction  nonsynonymous  peroxisome  ppardelta  progressive  proliferator  sequencing  unclear  ventricular 
17q  22cm  canine  centromeric  cfa9  correspond  cosmid  cryba1  distal  dog  grp78  hsa17  hsa17q  hsa9q  hsa9q34  hspa5  lies  linkage  loci  map  mmu2  nf1  occupy  painting  places  probable  syntenic  telomeric  thirds 
Tagcloud (Intersection) ?