NCOA6 and ASCC1

Number of citations of the paper that reports this interaction (PubMedID 10567404)
0

Data Source:
BioGRID (pull down)

		NCOA6	ASCC1
Description		nuclear receptor coactivator 6	activating signal cointegrator 1 complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Histone Methyltransferase Complex MLL3/4 Complex	Nucleus Nucleoplasm Transcription Regulator Complex Nuclear Speck DNA Repair Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity Protein Binding Enzyme Binding Nuclear Estrogen Receptor Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding	RNA Binding Protein Binding
	Biological Process	DNA-templated Transcription Initiation DNA Damage Response Brain Development Heart Development Response To Hormone Myeloid Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	DNA Replication DNA Repair DNA Alkylation Repair Regulation Of DNA-templated Transcription DNA Damage Response
Pathways		BMAL1:CLOCK,NPAS2 activates circadian expression PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Activation of anterior HOX genes in hindbrain development during early embryogenesis Cytoprotection by HMOX1 Heme signaling Formation of WDR5-containing histone-modifying complexes Epigenetic regulation of gene expression by MLL3 and MLL4 complexes MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis Expression of BMAL (ARNTL), CLOCK, and NPAS2 RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bipolar disorder ( 31043756) Coronary artery disease ( 29212778) Estimated glomerular filtration rate in non-diabetics ( 31451708) Feeling nervous ( 29500382) Fish- and plant-related diet ( 32066663) Height ( 28552196) Hip circumference adjusted for BMI ( 25673412 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Urate levels ( 31578528) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass index ( 30045251) Metabolite levels ( 23823483) Physiological traits ( 31902109)
Interacting Genes		63 interacting genes: AR ASCC1 ATF2 CD40 CEBPA CREBBP E2F1 EP300 ESR1 ESR2 FHOD1 FOS GHR GRIP1 GTF2A1 H3C14 HNF4A HSF1 JUN LAMTOR5 MED1 MED23 NCOR2 NFKB1 NR1H2 NR1H3 NR1H4 NR1I2 NR3C1 NUMA1 PARP1 PPARG PPARGC1A PRKDC PRMT2 RANBP9 RARA RB1 RBM14 RBM39 RELA RORB RORC RXRA RXRG SMAD2 SMAD3 SRC SRF TBP TGS1 THRA THRB TOP1 TRA TRB TXNRD2 UBC VDR XIAP XRCC5 XRCC6 ZNF335	6 interacting genes: ASCC3 NCOA6 OGT TRAF2 TRAF3 UBC
Entrez ID		23054	51008
HPRD ID		05599	12497
Ensembl ID		ENSG00000198646	ENSG00000138303
Uniprot IDs		F6M2K2 F6M2K3 Q14686	A0A5F9ZH79 A0A5K1VW55 Q8N9N2
PDB IDs			8TLY
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Chromatin Nuclear Receptor Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Nucleoplasm Positive Regulation Of Biosynthetic Process Intracellular Receptor Signaling Pathway Sequence-specific DNA Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-templated Transcription DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Regulator Complex Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Metabolic Process Chromatin DNA Binding Hormone-mediated Signaling Pathway Transcription Cis-regulatory Region Binding Chromatin Binding Intracellular Signal Transduction RNA Polymerase II-specific DNA-binding Transcription Factor Binding Response To Lipid Regulation Of Primary Metabolic Process Nuclear Receptor-mediated Signaling Pathway Nucleic Acid Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Polymerase II Transcription Regulator Complex Response To Hormone Negative Regulation Of Biosynthetic Process	Thioesterase Binding CD40 Receptor Complex Tumor Necrosis Factor Receptor Binding Ubiquitin Protein Ligase Binding TORC2 Complex Disassembly Tumor Necrosis Factor-mediated Signaling Pathway Signaling Adaptor Activity TOR Signaling TORC1 Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Ubiquitin Ligase Complex Cytoplasmic Side Of Plasma Membrane Protein Phosphatase Binding TRAF2-GSTP1 Complex TORC1 Complex Assembly Macromolecule Metabolic Process CD40 Receptor Binding Macromolecule Biosynthetic Process Protein Modification Process Response To Stress Protein Ubiquitination Cytosol Protein O-acetylglucosaminyltransferase Activity CAT Tailing RQC-trigger Complex Protein Modification By Small Protein Conjugation Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Regulation Of DNA-binding Transcription Factor Activity CD27 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cytoplasmic Translational Elongation Post-translational Protein Modification Catabolic Process Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Apoptotic Process Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Toll Signaling Pathway Carbon Catabolite Regulation Of Transcription Cell Death Programmed Cell Death Nucleoplasm Ubiquitin-protein Transferase Activity Regulation Of Transcription By Glucose Protein Ufmylation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?