TCEANC and FANCG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCEANC	FANCG
Description		transcription elongation factor A N-terminal and central domain containing	FA complementation group G
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Speck Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Damaged DNA Binding Protein Binding
	Biological Process	DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Ovarian Follicle Development DNA Repair DNA Damage Response Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair
Pathways			Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases			Fanconi anemia
GWAS			Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)
Interacting Genes		140 interacting genes: ADARB1 AKAP9 ANAPC11 APP ATXN1 AXIN2 BICD2 BRCA1 C1QTNF2 C8orf34 CARD9 CBY2 CCDC102B CCDC136 CCDC138 CCDC33 CCDC85B CCNC CDR2L CEP70 CEP76 CRACR2B CREB3L3 CSRNP1 CTAG1A CTAG1B CYSRT1 DAB1 DISC1 DMAP1 DTX3 DVL3 DYNLT1 EVI5 FAM217B FAM9B FANCG FBXO25 FCHO1 FSD2 GOLGA2 GOLGA6L9 HES7 HIP1 HMBOX1 HOMEZ HOOK2 IGF1 IKBKG IKZF2 IKZF3 KATNBL1 KCTD6 KCTD7 KIAA1958 KIF16B KIFC3 KLHL12 KRT31 KRT35 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP4-2 KRTAP5-9 L3MBTL3 LDOC1 LHX2 LHX3 LIN7B LMNA LSM14B LURAP1 MAGEA11 MCC MCIDAS MDFI MEOX1 MEOX2 MID1 MID2 MTUS2 MYF5 MYLIP NAB2 NECAB1 NEDD4 NINL OBI1 OOEP OSBPL3 PICK1 PLEKHF2 PNMA1 PNMA5 PXN RAD54B RNF41 RUBCN SIPA1L2 SORBS3 SSNA1 STRN3 STX1A STX4 TARBP2 TCP10L THAP1 TLE5 TMCO2 TNIP1 TNIP3 TRAF2 TRIM23 TRIM27 TRIM32 TRIM35 TRIM37 TRIM41 TRIM54 UBXN11 USH1G USHBP1 VAC14 VBP1 VPS52 YWHAE ZBTB14 ZBTB39 ZBTB9 ZFYVE26 ZKSCAN7 ZNF276 ZNF655 ZNF670 ZNF688 ZNF837 ZRANB1	44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1
Entrez ID		170082	2189
HPRD ID		19501	04262
Ensembl ID		ENSG00000176896	ENSG00000221829
Uniprot IDs		A8K5F6 B4DG85 Q8N8B7	O15287 Q53XM5
PDB IDs			7KZP 7KZQ 7KZR 7KZS 7KZT 7KZV
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Cytosol Intermediate Filament Post-translational Protein Modification Ubiquitin-protein Transferase Activity Keratin Filament Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cytoskeleton Regulation Of Transcription By RNA Polymerase II Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Zinc Ion Binding Suppression Of Viral Release By Host Regulation Of Viral Transcription Regulation Of Primary Metabolic Process Centrosome Cytoplasm Microtubule Binding Protein Monoubiquitination Regulation Of Organelle Organization Microtubule Regulation Of Cellular Component Organization Regulation Of Macromolecule Metabolic Process Protein Autoubiquitination Negative Regulation Of Viral Transcription Microtubule Cytoskeleton Organization Protein K63-linked Ubiquitination Nucleus Regulation Of Cytoskeleton Organization Enzyme Binding Signaling Adaptor Activity Protein Polyubiquitination Regulation Of Metabolic Process Intracellular Transport Somite Specification Response To Muramyl Dipeptide Establishment Of Localization In Cell Positive Regulation Of Catabolic Process Regulation Of Macromolecule Biosynthetic Process	DNA Metabolic Process DNA Damage Response DNA Repair Interstrand Cross-link Repair Fanconi Anaemia Nuclear Complex Mitotic G2 DNA Damage Checkpoint Signaling Telomere Maintenance Via Recombination Mitotic G2/M Transition Checkpoint Mitotic Recombination Nucleic Acid Metabolic Process Negative Regulation Of Cell Cycle G2/M Phase Transition Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Damage Checkpoint Signaling Female Gonad Development Signal Transduction In Response To DNA Damage Nucleoplasm Nuclear Ubiquitin Ligase Complex Chromosome, Telomeric Region Golgi Disassembly Cellular Response To Stress Telomere Maintenance DNA Damage Checkpoint Signaling Regulation Of Glycoprotein Biosynthetic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle BRCA1-A Complex Chromosome Organization Centrosome Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Double-strand Break Repair Regulation Of Cell Cycle Positive Regulation Of Glutamate Receptor Signaling Pathway Telomere Organization Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Gonad Development Regulation Of Lymphoid Progenitor Cell Differentiation Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Primary Metabolic Process Meiosis I Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Nucleus Cellular Response To Radiation Organelle Organization Regulation Of Embryonic Development Microtubule Organizing Center Organization Chromatin Reproductive Structure Development
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