FOXG1 and EEF1G

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FOXG1	EEF1G
Gene Name		forkhead box G1	eukaryotic translation elongation factor 1 gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Translation Elongation Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Brain Development Aging Negative Regulation Of Transcription, DNA-templated	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process
Pathways			Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS		Longevity ( 20834067) Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		16 interactors: APOE EEF1G FOXH1 FOXO1 FOXO3 FOXO4 GDF9 HDAC1 HES1 KDM5B SMAD1 SMAD2 SMAD3 SMAD4 TLE1 TLE3	87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		2290	1937
HPRD ID		01283	11745
Ensembl ID		ENSG00000176165	ENSG00000254772
Uniprot IDs		P55316	P26641 Q53YD7
PDB IDs			1PBU
Enriched GO Terms of Interacting Partners?		Cellular Response To Growth Factor Stimulus Response To Growth Factor Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway SMAD Protein Complex Assembly Cellular Macromolecule Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Macromolecule Biosynthetic Process Response To Transforming Growth Factor Beta Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway Cell Surface Receptor Signaling Pathway RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Proliferation Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Primary MiRNA Processing Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Differentiation Mesonephros Development Organ Development Mesoderm Development Anatomical Structure Development Cardiovascular System Development	Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity
Tagcloud ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 gadd45a gadd45b hdac11 homer1 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1	4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Difference) ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 gadd45a gadd45b hdac11 homer1 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1	4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Intersection) ?