ICK and BAG6

Number of citations of the paper that reports this interaction (PMID 16954377)
19

Data Source:
BioGRID (enzymatic study)

		ICK	BAG6
Gene Name		intestinal cell (MAK-like) kinase	BCL2-associated athanogene 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Ciliary Basal Body Ciliary Tip	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle BAT3 Complex
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding Hsp70 Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ribosome Binding Proteasome Binding
	Biological Process	Protein Phosphorylation Signal Transduction Multicellular Organismal Development Intracellular Signal Transduction Intraciliary Transport Cilium Assembly Regulation Of Cell Cycle	Kidney Development Immune System Process Ubiquitin-dependent Protein Catabolic Process Transport Synaptonemal Complex Assembly Spermatogenesis Brain Development Embryo Development Chromatin Modification Internal Peptidyl-lysine Acetylation Cell Differentiation Lung Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Protein Stabilization Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS			Schizophrenia ( 23894747)
Protein-Protein Interactions		5 interactors: APP BAG6 CDK20 RPTOR SMAD1	102 interactors: ACVR1B AMFR ANXA7 ARPC3 ATN1 ATXN2 B2M C1QA CD93 CDK16 CDK4 CDK5 CDKN1A CHN2 CLU CSNK2B CSTF2 CTCFL CTSB CTSE CTSL CXCL8 DNAJB11 DPT EDN1 EFEMP1 EFEMP2 EP300 FAM173A FAM46A FAM9B FAS FKBP2 FZD4 GADD45A GLRA2 GSK3B HSPA13 HSPA8 ICK IGF2 IGFBP5 IKBKAP IMMT IQCG KLHL12 LBP LPPR3 MAPK6 MAVS MEST MYDGF NBL1 NCR3 NDUFA6 NDUFB11 NOMO1 NPY NR1H2 PELP1 PIN1 PLA2G2A PLK1 POLR2J PPAP2C PRMT2 PRNP PRPF40A PTH PTN PTPN12 RAB8A RAC1 RCC1 RCN2 REG1B RNF126 S100A4 SDC2 SEC61A1 SEC61B SERPING1 SERPINH1 SETDB1 SGTA SMN1 SPP1 SRGN STX5 TAC1 TDGF1 TFCP2 TK1 TOMM20 TP63 TTR UBL4A UBL7 UBQLN4 VAMP2 XRN1 ZFYVE9
Entrez ID		22858	7917
HPRD ID		09996	00808
Ensembl ID		ENSG00000112144	ENSG00000204463
Uniprot IDs		B3KQG4 Q9UPZ9	P46379
PDB IDs			1WX9 4DWF 4EEW
Enriched GO Terms of Interacting Partners?		Posttranscriptional Regulation Of Gene Expression Growth Brain Development Sexual Reproduction Head Development Cell Growth Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Collateral Sprouting In Absence Of Injury Central Nervous System Development Reproduction Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Primary MiRNA Processing Axon Choice Point Recognition Tail-anchored Membrane Protein Insertion Into ER Membrane Osteoblast Fate Commitment Cellular Protein Modification Process Reproductive Process Positive Regulation Of Transcription, DNA-templated Protein Phosphorylation Kidney Development Cell Cycle Protein Insertion Into ER Membrane Renal System Development Neuron Remodeling Response To Stress Positive Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Proteolysis Regulation Of Cell Proliferation Negative Regulation Of Protein Processing Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Complex Assembly Urogenital System Development Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Processing Mesodermal Cell Fate Commitment Cellular Copper Ion Homeostasis Cardiac Muscle Cell Proliferation Intracellular Signal Transduction Phosphorylation Protein Insertion Into Membrane TOR Signaling Cellular Component Assembly Production Of MiRNAs Involved In Gene Silencing By MiRNA Positive Regulation Of TOR Signaling Synaptonemal Complex Assembly Cellular Response To BMP Stimulus	Response To Organic Substance Response To Stress Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Protein Phosphorylation Immune Response Regulation Of Immune System Process Regulation Of Protein Phosphorylation Cellular Response To Stimulus Defense Response Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Cell Cycle Response To External Stimulus Signal Transduction Developmental Process Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Positive Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cell Development System Development Regulation Of Phosphorylation Regulation Of Signal Transduction Response To Hormone Immune System Process Response To Lipid Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Protein Metabolic Process Regulation Of Cellular Process Cellular Process Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Motility Apoptotic Signaling Pathway Multicellular Organismal Development Positive Regulation Of Signal Transduction
Tagcloud ?		allergen astacin biotechnological bites brown continents cystine dermonecrosis gravitational hemolysis hyaluronidases intravascular knot loxosceles loxoscelism manifestations metalloproteases noxious occasional phospholipases spider spiders spreading tctp thrombocytopenia toxins translationally venom venoms	biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		allergen astacin biotechnological bites brown continents cystine dermonecrosis gravitational hemolysis hyaluronidases intravascular knot loxosceles loxoscelism manifestations metalloproteases noxious occasional phospholipases spider spiders spreading tctp thrombocytopenia toxins translationally venom venoms	biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?