OAZ3

Description		ornithine decarboxylase antizyme 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Sperm Flagellum Blood Microparticle
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity Ankyrin Repeat Binding
	Biological Process	Polyamine Biosynthetic Process Spermatogenesis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Stress Fiber Assembly Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs
Diseases
GWAS		Asthma ( 31619474) Carotid plaque burden ( 28282560) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566)
Novel Interacting Genes		1 novel interacting genes: CD48
Interacting Genes		14 interacting genes: AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 POMC POU6F2 REL SMAD1 TEPSIN ZBTB42 ZNF620
Entrez ID		51686
HPRD ID		18670
Ensembl ID		ENSG00000143450
Uniprot IDs		A0A0G2JH29 H0Y7Y4 Q9UMX2
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyamine Biosynthetic Process Polyamine Metabolic Process Regulation Of DNA-templated Transcription Mesodermal Cell Fate Commitment Regulation Of Primary Metabolic Process Homomeric SMAD Protein Complex Osteoblast Fate Commitment Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Binding DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Amine Biosynthetic Process Ornithine Decarboxylase Inhibitor Activity Biogenic Amine Biosynthetic Process Amine Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Biogenic Amine Metabolic Process Positive Regulation Of Neutrophil Mediated Killing Of Fungus Positive Regulation Of Oxytocin Production Response To Melanocyte-stimulating Hormone Cis-Golgi Network Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Methylation-dependent Protein Binding Ornithine Decarboxylase Activator Activity Arginine Decarboxylase Activity Granular Vesicle Agmatine Biosynthetic Process Ornithine Decarboxylase Activity Positive Regulation Of Polyamine Transmembrane Transport Putrescine Biosynthetic Process From Arginine, Via Ornithine Trans-Golgi Network Membrane Organization Coated Vesicle Membrane Regulation Of Transcription By RNA Polymerase II Cellular Pigmentation Type 1 Melanocortin Receptor Binding Type 4 Melanocortin Receptor Binding Positive Regulation Of Killing Of Cells Of Another Organism Type 3 Melanocortin Receptor Binding NF-kappaB Complex Ornithine Metabolic Process Anti-Mullerian Hormone Receptor Signaling Pathway Regulation Of RNA Metabolic Process Putrescine Biosynthetic Process Regulation Of Corticosterone Secretion Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity
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