OAZ3 and OAZ1

Number of citations of the paper that reports this interaction (PMID 15355308)
8

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		OAZ3	OAZ1
Gene Name		ornithine decarboxylase antizyme 3	ornithine decarboxylase antizyme 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Sperm Flagellum Blood Microparticle	Cytosol
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity Putrescine Transmembrane Transporter Activity Ankyrin Repeat Binding	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Biosynthetic Process Spermatogenesis Putrescine Transport Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Polyamine Transmembrane Transport	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Biosynthetic Process Transport Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives	Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives
Drugs			L-Ornithine
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AZIN1 AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 ODC1 REL SMAD1	8 interactors: ATXN1 EGFR OAZ2 OAZ3 ODC1 PIAS4 PSMB4 SMAD1
Entrez ID		51686	4946
HPRD ID		18670	03346
Ensembl ID		ENSG00000143450	ENSG00000104904
Uniprot IDs		Q6GMR0 Q9UMX2	P54368
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Cellular Biogenic Amine Metabolic Process Positive Regulation Of Polyamine Transmembrane Transport Amine Metabolic Process Ornithine Metabolic Process Regulation Of Protein Catabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Trans-Golgi Network Membrane Organization Putrescine Biosynthetic Process From Ornithine Regulation Of Cellular Amino Acid Metabolic Process Putrescine Transport Agmatine Biosynthetic Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Putrescine Biosynthetic Process Mesoderm Development Negative Regulation Of Polyamine Transmembrane Transport Gamete Generation Primary MiRNA Processing Positive Regulation Of Transport Osteoblast Fate Commitment Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Transcription From RNA Polymerase II Promoter SMAD Protein Complex Assembly Positive Regulation Of Interleukin-12 Biosynthetic Process Erythrocyte Maturation Alpha-amino Acid Metabolic Process Mesodermal Cell Fate Commitment Granulocyte Differentiation Kidney Development Regulation Of Interleukin-12 Biosynthetic Process Reproduction Renal System Development Positive Regulation Of Metabolic Process Macrophage Differentiation Cardiac Muscle Cell Proliferation Golgi To Plasma Membrane Protein Transport Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Urogenital System Development Regulation Of Cellular Process	Polyamine Biosynthetic Process Amine Biosynthetic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Regulation Of Nitrogen Compound Metabolic Process Cellular Biogenic Amine Metabolic Process Positive Regulation Of Metabolic Process Amine Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Biosynthetic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Transport Positive Regulation Of Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Alkanesulfonate Metabolic Process Putrescine Biosynthetic Process From Ornithine Positive Regulation Of Cellular Metabolic Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Keratinocyte Apoptotic Process Putrescine Transport Astrocyte Activation Regulation Of Response To DNA Damage Stimulus Regulation Of Apoptotic Process Putrescine Biosynthetic Process Regulation Of Cell Death Cellular Metabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Intracellular Protein Transport Tube Development Activation Of Phospholipase A2 Activity Positive Regulation Of Phospholipase A2 Activity Negative Regulation Of Catalytic Activity Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Reproductive Process Response To Cobalamin Response To UV-A Primary MiRNA Processing Multicellular Organism Reproduction Response To Hydroxyisoflavone Negative Regulation Of Mitotic Cell Cycle MAPK Cascade Gene Expression Ornithine Metabolic Process Osteoblast Fate Commitment
Tagcloud ?		abundance affymetrix anxa2 arrays asthenozoospermia asthenozoospermic brd2 characterizing consider equal fertile hybridized implication infertile infertility microarrays motility project reach rnas sperm started subsequently teratozoospermic transcripts u133 utility validated version	anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 srsf9 stimuli tardbp thoughts top tsp
Tagcloud (Difference) ?		abundance affymetrix anxa2 arrays asthenozoospermia asthenozoospermic brd2 characterizing consider equal fertile hybridized implication infertile infertility microarrays motility project reach rnas sperm started subsequently teratozoospermic transcripts u133 utility validated version	anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 srsf9 stimuli tardbp thoughts top tsp
Tagcloud (Intersection) ?