OAZ3 and AZIN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OAZ3	AZIN2
Description		ornithine decarboxylase antizyme 3	antizyme inhibitor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Sperm Flagellum Blood Microparticle	Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Trans-Golgi Network Cytosol Membrane Transport Vesicle Axon Dendrite Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cell Projection Perikaryon Perinuclear Region Of Cytoplasm Granular Vesicle
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity Ankyrin Repeat Binding	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Arginine Decarboxylase Activity Carboxy-lyase Activity Ornithine Decarboxylase Activator Activity
	Biological Process	Polyamine Biosynthetic Process Spermatogenesis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Stress Fiber Assembly Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Ornithine Metabolic Process Polyamine Biosynthetic Process Spermatogenesis Putrescine Biosynthetic Process From Arginine, Via Ornithine Negative Regulation Of Protein Catabolic Process Positive Regulation Of Catalytic Activity Agmatine Biosynthetic Process Trans-Golgi Network Membrane Organization Positive Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Agmatine biosynthesis
Drugs			Pyridoxal phosphate Arginine Benzoyl peroxide
Diseases
GWAS		Asthma ( 31619474) Carotid plaque burden ( 28282560) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566)	Pursuit maintenance gain ( 29064472)
Interacting Genes		14 interacting genes: AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 POMC POU6F2 REL SMAD1 TEPSIN ZBTB42 ZNF620	3 interacting genes: OAZ3 PSMC5 TLN1
Entrez ID		51686	113451
HPRD ID		18670	17657
Ensembl ID		ENSG00000143450	ENSG00000142920
Uniprot IDs		A0A0G2JH29 H0Y7Y4 Q9UMX2	Q96A70
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyamine Biosynthetic Process Polyamine Metabolic Process Regulation Of DNA-templated Transcription Mesodermal Cell Fate Commitment Regulation Of Primary Metabolic Process Homomeric SMAD Protein Complex Osteoblast Fate Commitment Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Binding DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Amine Biosynthetic Process Ornithine Decarboxylase Inhibitor Activity Biogenic Amine Biosynthetic Process Amine Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Biogenic Amine Metabolic Process Positive Regulation Of Neutrophil Mediated Killing Of Fungus Positive Regulation Of Oxytocin Production Response To Melanocyte-stimulating Hormone Cis-Golgi Network Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Methylation-dependent Protein Binding Ornithine Decarboxylase Activator Activity Arginine Decarboxylase Activity Granular Vesicle Agmatine Biosynthetic Process Ornithine Decarboxylase Activity Positive Regulation Of Polyamine Transmembrane Transport Putrescine Biosynthetic Process From Arginine, Via Ornithine Trans-Golgi Network Membrane Organization Coated Vesicle Membrane Regulation Of Transcription By RNA Polymerase II Cellular Pigmentation Type 1 Melanocortin Receptor Binding Type 4 Melanocortin Receptor Binding Positive Regulation Of Killing Of Cells Of Another Organism Type 3 Melanocortin Receptor Binding NF-kappaB Complex Ornithine Metabolic Process Anti-Mullerian Hormone Receptor Signaling Pathway Regulation Of RNA Metabolic Process Putrescine Biosynthetic Process Regulation Of Corticosterone Secretion Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity	Nuclear Proteasome Complex Blood Microparticle Thyrotropin-releasing Hormone Receptor Binding Positive Regulation Of Protein Catabolic Process Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Proteasome-activating Activity Cytosolic Proteasome Complex Positive Regulation Of Inclusion Body Assembly LIM Domain Binding Ankyrin Repeat Binding Viral Translational Frameshifting Regulation Of Protein Catabolic Process Cortical Microtubule Organization Proteasome Regulatory Particle, Base Subcomplex General Transcription Initiation Factor Binding Proteasome Regulatory Particle Vinculin Binding Integrin Activation Polyamine Biosynthetic Process Regulation Of Cellular Component Organization Proteasome Accessory Complex Positive Regulation Of Catabolic Process Polyamine Metabolic Process Inclusion Body Transcription Factor Binding Regulation Of Inclusion Body Assembly TBP-class Protein Binding Cortical Actin Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Metabolic Process Amine Biosynthetic Process Negative Regulation Of Actin Filament Bundle Assembly Biogenic Amine Biosynthetic Process Cell-substrate Junction Assembly Cell-substrate Junction Organization Cortical Cytoskeleton Organization Platelet Aggregation
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