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FAM124A and PRKG1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
FAM124A
PRKG1
Gene Name
family with sequence similarity 124A
protein kinase, cGMP-dependent, type I
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Molecular Function
CGMP-dependent Protein Kinase Activity
Calcium Channel Regulator Activity
Protein Binding
ATP Binding
CGMP Binding
Biological Process
Neuron Migration
Protein Phosphorylation
Signal Transduction
Blood Coagulation
Dendrite Development
CGMP-mediated Signaling
Actin Cytoskeleton Organization
Forebrain Development
Regulation Of GTPase Activity
Relaxation Of Vascular Smooth Muscle
Negative Regulation Of Platelet Aggregation
Pathways
Ca2+ pathway
Signaling by Wnt
beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Asthma (
21907864
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
27 interactors:
AES
CCDC33
CCDC36
CEP70
CGGBP1
DOCK8
FAM154A
FOXP2
INO80E
KIFC3
LNX1
NKAP
PHC2
PRKG1
RAB3IP
RBM10
ROCK1
SRPK1
STAC3
THAP1
TRIM41
TRIM54
ZBTB44
ZFP64
ZNF165
ZNF250
ZZZ3
34 interactors:
ANXA7
CFTR
CREB1
CRIP2
FAM124A
FHOD1
GABRR1
GKAP1
GTF2I
HDAC1
ITPR1
LASP1
LMO2
MRVI1
NPR1
PDE5A
PLCB3
PPP1R12A
PPP1R12B
PPP1R17
PRKCA
RAF1
RGS2
RYR1
SELL
SEPT3
SF1
SPP1
TBXA2R
TNNT1
TRIM39-RPP21
TRPC3
VASP
ZNF646
Entrez ID
220108
5592
HPRD ID
08704
08910
Ensembl ID
ENSG00000150510
ENSG00000185532
Uniprot IDs
Q86V42
Q13976
PDB IDs
1ZXA
3NMD
3OCP
3OD0
3OGJ
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Transcription, DNA-templated
Gene Expression
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Nitrogen Compound Metabolic Process
Putamen Development
Caudate Nucleus Development
Memory T Cell Proliferation
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Single Organismal Cell-cell Adhesion
Regulation Of MRNA Splicing, Via Spliceosome
Muscle System Process
Zonula Adherens Maintenance
Regulation Of MRNA Processing
Biosynthetic Process
Leukocyte Cell-cell Adhesion
Positive Regulation Of Anoikis
Cellular Metabolic Process
Regulation Of RNA Splicing
Membrane To Membrane Docking
Vocal Learning
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Apical Constriction
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Righting Reflex
Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Regulation Of Body Fluid Levels
Hemostasis
Regulation Of Muscle Contraction
Blood Coagulation
Negative Regulation Of Muscle Contraction
Regulation Of Cardiac Muscle Hypertrophy
Wound Healing
Response To Wounding
Cellular Response To Stimulus
Response To Stimulus
Positive Regulation Of Cardiac Muscle Hypertrophy
Regulation Of Cellular Process
Response To Organic Substance
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Cellular Calcium Ion Homeostasis
Relaxation Of Muscle
Calcium Ion Homeostasis
Regulation Of Blood Vessel Size
Regulation Of Tube Size
Blood Circulation
Signal Transduction
Cellular Chemical Homeostasis
Regulation Of Phospholipase Activity
Platelet Activation
Ion Homeostasis
Neurotrophin TRK Receptor Signaling Pathway
Vasodilation
Neurotrophin Signaling Pathway
Cellular Metal Ion Homeostasis
Signaling
Cell Communication
Muscle System Process
Cellular Homeostasis
Metal Ion Homeostasis
Relaxation Of Vascular Smooth Muscle
Activation Of Phospholipase C Activity
Positive Regulation Of Metabolic Process
Regulation Of Smooth Muscle Contraction
Relaxation Of Smooth Muscle
Positive Regulation Of Phospholipase C Activity
Regulation Of Ion Homeostasis
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Purine-containing Compound
Cytosolic Calcium Ion Homeostasis
Chemical Homeostasis
Cellular Response To Fibroblast Growth Factor Stimulus
Relaxation Of Cardiac Muscle
Tagcloud
?
1n9c
acsl3
agpat3
bovinesnp50
bta1
c10
c12
c14
c18
chuk
dgat1
echs1
ehhadh
groundwork
htr1b
lipj
lipk
minpp1
mogat1
nfkb2
osbpl8
oxct1
plink
scd1
sfa
sorbs1
ufa
underling
unraveling
Tagcloud (Difference)
?
1n9c
acsl3
agpat3
bovinesnp50
bta1
c10
c12
c14
c18
chuk
dgat1
echs1
ehhadh
groundwork
htr1b
lipj
lipk
minpp1
mogat1
nfkb2
osbpl8
oxct1
plink
scd1
sfa
sorbs1
ufa
underling
unraveling
Tagcloud (Intersection)
?