FAM124A and FOXP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM124A	FOXP2
Gene Name		family with sequence similarity 124A	forkhead box P2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus
	Molecular Function		RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesenchymal Cell Proliferation Transcription, DNA-templated Skeletal Muscle Tissue Development Post-embryonic Development Cerebellum Development Caudate Nucleus Development Putamen Development Cerebral Cortex Development Growth Vocal Learning Camera-type Eye Development Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development Smooth Muscle Tissue Development Righting Reflex Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 22936669)
Protein-Protein Interactions		27 interactors: AES CCDC33 CCDC36 CEP70 CGGBP1 DOCK8 FAM154A FOXP2 INO80E KIFC3 LNX1 NKAP PHC2 PRKG1 RAB3IP RBM10 ROCK1 SRPK1 STAC3 THAP1 TRIM41 TRIM54 ZBTB44 ZFP64 ZNF165 ZNF250 ZZZ3	13 interactors: AES CCNC CTBP1 CTBP2 FAM124A FOXP1 FOXP4 MAPK3 PIN1 RPIA SDCBP SP4 TSACC
Entrez ID		220108	93986
HPRD ID		08704	05611
Ensembl ID		ENSG00000150510	ENSG00000128573
Uniprot IDs		Q86V42	B7ZLK5 O15409 Q8N6B5 Q8N6B6
PDB IDs			2A07 2AS5
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Putamen Development Caudate Nucleus Development Memory T Cell Proliferation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Single Organismal Cell-cell Adhesion Regulation Of MRNA Splicing, Via Spliceosome Muscle System Process Zonula Adherens Maintenance Regulation Of MRNA Processing Biosynthetic Process Leukocyte Cell-cell Adhesion Positive Regulation Of Anoikis Cellular Metabolic Process Regulation Of RNA Splicing Membrane To Membrane Docking Vocal Learning Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Apical Constriction Negative Regulation Of Transcription From RNA Polymerase II Promoter Righting Reflex Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis	Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Lung Goblet Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Lung Secretory Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Transcription From RNA Polymerase II Promoter White Fat Cell Differentiation Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Viral Genome Replication Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Epithelial Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Regulation Of Binding Negative Regulation Of Biosynthetic Process Regulation Of Histone Acetylation Positive Regulation Of Metabolic Process Biosynthetic Process Negative Regulation Of Protein Binding Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Lung Epithelial Cell Differentiation Lung Cell Differentiation Lung Epithelium Development Interleukin-21 Secretion Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Histone Modification Regulation Of Organelle Organization Axon Guidance Regulation Of Signal Transduction Response To Interleukin-1 Positive Regulation Of Organelle Organization
Tagcloud ?			20p12 21q22 22q13 42e 6p21 7q31 aif1 ancestry cd crohn cumulative ep300 european exerted genotyped gwas ifngr2 intergenic likelihood loci macrod2 rbx1 representing rs4820425 southern spain suggestive top undiscovered
Tagcloud (Difference) ?			20p12 21q22 22q13 42e 6p21 7q31 aif1 ancestry cd crohn cumulative ep300 european exerted genotyped gwas ifngr2 intergenic likelihood loci macrod2 rbx1 representing rs4820425 southern spain suggestive top undiscovered
Tagcloud (Intersection) ?