FAM124A and INO80E

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM124A	INO80E
Description		family with sequence similarity 124 member A	INO80 complex subunit E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Ino80 Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Positive Regulation Of Telomere Maintenance In Response To DNA Damage
Pathways			UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease ( 34020725) Cerebrospinal fluid clusterin levels ( 26545630) Lipoprotein (a) levels ( 30108283) Metabolite levels ( 23823483) Placental abruption ( 29884306) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-negative) ( 24532677)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Schizophrenia ( 25056061 28991256 29483656)
Interacting Genes		30 interacting genes: BEND7 CCDC33 CEP70 CGGBP1 DOCK8 FOXP2 IHO1 IL16 INO80E KIFC3 LNX1 NCK2 NKAP PHC2 PRKG1 RAB3IP RBM10 ROCK1 SAXO1 SRPK1 STAC3 THAP1 TLE5 TRIM41 TRIM54 ZBTB44 ZFP64 ZNF165 ZNF250 ZZZ3	21 interacting genes: APPL1 CDC23 CRK FAM124A FAM161A GEM IKBKG KPNA2 LNX1 MAB21L3 MORN4 NHLH1 PHF19 PICK1 PIN1 PRKAA1 PSMA1 SDCBP TBRG1 TLE5 TNFAIP8
Entrez ID		220108	283899
HPRD ID		08704	08816
Ensembl ID		ENSG00000150510	ENSG00000169592
Uniprot IDs		Q86V42	J3KNE2 Q8NBZ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Zinc Ion Binding
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