MED28 and MIIP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MED28	MIIP
Description		mediator complex subunit 28	migration and invasion inhibitory protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Membrane Mediator Complex Cortical Actin Cytoskeleton Core Mediator Complex
	Molecular Function	Actin Binding Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance RNA Polymerase II Preinitiation Complex Assembly Negative Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Transcription Initiation By RNA Polymerase II	Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Migration
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs
Diseases
GWAS			Asthma ( 31959851) Serum alkaline phosphatase levels ( 33339817) Tuberculosis ( 29036319)
Interacting Genes		18 interacting genes: CBY2 CEBPA FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 MIIP NF2 PRMT6 PUF60 SRC SUOX TCP11 USHBP1	25 interacting genes: BCAS2 CCDC120 CYSRT1 EFHC1 EIF3E FRS3 ITGB3 KCTD9 KPRP KRT34 MED28 MOB2 OIP5 OTX1 PPP1CA STK16 TCHP TEKT4 TLE5 TRIM55 TRIM63 TRIP6 USHBP1 ZDHHC17 ZNF417
Entrez ID		80306	60672
HPRD ID		14381	07768
Ensembl ID		ENSG00000118579	ENSG00000116691
Uniprot IDs		Q9H204	Q5JXC2
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Phospholipase Activator Activity T Cell Costimulation Positive Regulation Of DNA-templated Transcription Initiation Phospholipase Binding Regulation Of DNA-templated Transcription Initiation Core Mediator Complex Ephrin Receptor Binding CD8 Receptor Binding Fc-gamma Receptor Signaling Pathway Mediator Complex Non-membrane Spanning Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation RNA Polymerase II Preinitiation Complex Assembly Regulation Of Protein Localization To Nucleus Fc Receptor Signaling Pathway Positive Regulation Of Transcription Elongation By RNA Polymerase II CD4 Receptor Binding Transcription Preinitiation Complex Assembly Protein-containing Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Cell Activation T Cell Receptor Binding Scaffold Protein Binding Regulation Of Transcription Initiation By RNA Polymerase II Identical Protein Binding Activation Of Immune Response Protein-containing Complex Organization Interleukin-6-mediated Signaling Pathway Phosphatidylinositol 3-kinase Binding Protein Phosphatase Binding Regulation Of Transcription Elongation By RNA Polymerase II Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of T Cell Activation Angiotensin-activated Signaling Pathway Regulation Of DNA-templated Transcription Elongation Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Regulation Of Cell-cell Adhesion Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Leukocyte Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Protein Import Into Mitochondrial Matrix Response To Xenobiotic Stimulus Disordered Domain Specific Binding
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