MED28 and PUF60

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MED28	PUF60
Gene Name		mediator complex subunit 28	poly-U binding splicing factor 60KDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Mediator Complex Cortical Actin Cytoskeleton	Nucleoplasm Mitochondrion Golgi Apparatus Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex Ribonucleoprotein Complex
	Molecular Function	Actin Binding Protein Binding	Nucleotide Binding DNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Stem Cell Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Apoptotic Process RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 NF2 PRMT6 PUF60 SPERT SRC USHBP1	30 interactors: ARL8A CACNA1A CCNC CD101 CHD3 ERG FHL2 FUBP1 HIST1H1C ID3 KIAA0907 KIAA1683 LOH12CR1 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16
Entrez ID		80306	22827
HPRD ID		14381	18051
Ensembl ID			ENSG00000179950
Uniprot IDs		Q9H204	Q9UHX1
PDB IDs			2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Cell-cell Adhesion Peptidyl-tyrosine Autophosphorylation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Viral Process Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Gene Expression Blood Coagulation Phosphatidylinositol-mediated Signaling Hemostasis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Response To Peptide Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Defense Response To Virus By Virus Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Protein Autophosphorylation Regulation Of Body Fluid Levels Negative Regulation Of Signaling Response To Mechanical Stimulus Response To Growth Factor	RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Processing MRNA 3'-end Processing RNA 3'-end Processing Negative Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Nuclear Export MRNA Transport RNA Processing Regulation Of Metabolic Process RNA Transport RNA Localization Regulation Of Gene Expression Membrane Depolarization During Action Potential Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Death Negative Regulation Of Muscle Cell Differentiation Cerebellar Molecular Layer Development Negative Regulation Of Potassium Ion Export Positive Regulation Of SUMO Transferase Activity Vestibular Nucleus Development Nucleotide-excision Repair, DNA Damage Recognition Regulation Of Heart Rate By Hormone Negative Regulation Of Gene Expression Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Cerebellum Maturation Atrial Cardiac Muscle Cell Development Musculoskeletal Movement, Spinal Reflex Action Regulation Of Apoptotic Process
Tagcloud ?		aspect blocked concomitant construct cytoskeleton dead ectopic eg exhibits exogenous grb2 interfering invasion magicin map2k1 mediator mek1 merlin metalloproteinase migration mmp2 potentiated presumably recovered reinforcing repressor rescued stimulate suppression	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Difference) ?		aspect blocked concomitant construct cytoskeleton dead ectopic eg exhibits exogenous grb2 interfering invasion magicin map2k1 mediator mek1 merlin metalloproteinase migration mmp2 potentiated presumably recovered reinforcing repressor rescued stimulate suppression	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Intersection) ?