MED28 and MED9

Number of citations of the paper that reports this interaction (PMID 20133760)
29

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		MED28	MED9
Gene Name		mediator complex subunit 28	mediator complex subunit 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Mediator Complex Cortical Actin Cytoskeleton	Mediator Complex
	Molecular Function	Actin Binding Protein Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Stem Cell Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 NF2 PRMT6 PUF60 SPERT SRC USHBP1	26 interactors: APP CBX4 CDK8 MED1 MED11 MED12 MED13 MED14 MED16 MED18 MED19 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 USP47
Entrez ID		80306	55090
HPRD ID		14381	14383
Ensembl ID			ENSG00000141026
Uniprot IDs		Q9H204	Q9NWA0
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Costimulation Regulation Of Cell-cell Adhesion Peptidyl-tyrosine Autophosphorylation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Viral Process Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Gene Expression Blood Coagulation Phosphatidylinositol-mediated Signaling Hemostasis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Response To Peptide Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Defense Response To Virus By Virus Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Protein Autophosphorylation Regulation Of Body Fluid Levels Negative Regulation Of Signaling Response To Mechanical Stimulus Response To Growth Factor	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Androgen Receptor Signaling Pathway Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Stem Cell Maintenance Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Stem Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Gene Expression Stem Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Differentiation Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Differentiation Cell Development Positive Regulation Of Metabolic Process Regulation Of Receptor Activity Cellular Process Developmental Growth Involved In Morphogenesis Negative Regulation Of Fibroblast Proliferation Axis Elongation Positive Regulation Of Receptor Activity Regulation Of G2/M Transition Of Mitotic Cell Cycle Thyroid Hormone Mediated Signaling Pathway
Tagcloud ?		aspect blocked concomitant construct cytoskeleton dead ectopic eg exhibits exogenous grb2 interfering invasion magicin map2k1 mediator mek1 merlin metalloproteinase migration mmp2 potentiated presumably recovered reinforcing repressor rescued stimulate suppression
Tagcloud (Difference) ?		aspect blocked concomitant construct cytoskeleton dead ectopic eg exhibits exogenous grb2 interfering invasion magicin map2k1 mediator mek1 merlin metalloproteinase migration mmp2 potentiated presumably recovered reinforcing repressor rescued stimulate suppression
Tagcloud (Intersection) ?