FANCC and RPL18

Number of citations of the paper that reports this interaction (PMID 14499622)
5

Data Source:
BioGRID (two hybrid)

		FANCC	RPL18
Gene Name		Fanconi anemia, complementation group C	ribosomal protein L18
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	Protein Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Protein Complex Assembly Germ Cell Development Removal Of Superoxide Radicals	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Fanconi Anemia pathway	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		27 interactors: ATP6 AZIN1 CAPN10 CDK1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 POR RPL18 RPS3A SPTA1 SPTAN1 STAT1 TCERG1 USP14 ZBTB32	4 interactors: CDKN1A FANCA FANCC IL7R
Entrez ID		2176	6141
HPRD ID		01967	16046
Ensembl ID		ENSG00000158169	ENSG00000063177
Uniprot IDs		B4E3W2 Q00597	F8VWC5 Q07020
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Protein Refolding Response To Unfolded Protein Cellular Response To Stress Regulation Of Cellular Response To Heat Response To Stress Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Heat DNA Repair Response To Stimulus Protein Import Into Mitochondrial Outer Membrane Response To Heat Protein Folding Response To Abiotic Stimulus Cellular Response To DNA Damage Stimulus Membrane Organization Cellular Metabolic Process Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Inclusion Body Assembly Response To Temperature Stimulus Axon Guidance Response To Oxidative Stress Response To External Stimulus Chaperone-mediated Protein Complex Assembly DNA Metabolic Process Establishment Of Protein Localization To Membrane Nucleobase-containing Compound Metabolic Process Chaperone Mediated Protein Folding Requiring Cofactor Regulation Of Apoptotic Process Cellular Response To Organonitrogen Compound Regulation Of Inclusion Body Assembly Regulation Of Cell Death Protein Localization To Organelle Female Gonad Development Axonogenesis Development Of Primary Female Sexual Characteristics Cellular Macromolecule Catabolic Process Viral Process Cellular Response To Peptide Hormone Stimulus Axon Development Positive Regulation Of Immune System Process Negative Regulation Of Apoptotic Process Cellular Response To Peptide Nitric Oxide Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Immune System Process Negative Regulation Of Programmed Cell Death Metabolic Process	Cellular Response To DNA Damage Stimulus Interleukin-7-mediated Signaling Pathway Homeostasis Of Number Of Cells Negative Regulation Of T Cell Mediated Cytotoxicity Intestinal Epithelial Cell Maturation Positive Regulation Of Cell Activation Cellular Response To Stress Cellular Response To UV-B Regulation Of Lymphocyte Activation Stress-induced Premature Senescence Anatomical Structure Development Negative Regulation Of T Cell Mediated Immunity Regulation Of Cell Activation Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Immune System Process Developmental Process Regulation Of Protein Import Into Nucleus, Translocation Removal Of Superoxide Radicals Intestinal Epithelial Cell Differentiation Cellular Response To Superoxide Epithelial Cell Maturation DNA Repair Response To Superoxide Response To Arsenic-containing Substance Response To Oxygen Radical Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Senescence Regulation Of T Cell Differentiation In Thymus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Developmental Process Involved In Reproduction Response To Hyperoxia Response To Corticosterone Negative Regulation Of Adaptive Immune Response Cellular Response To Stimulus Response To Mineralocorticoid B Cell Proliferation Positive Regulation Of B Cell Proliferation Superoxide Metabolic Process Organ Development Regulation Of Immune Response Columnar/cuboidal Epithelial Cell Development Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA Biosynthetic Process Positive Regulation Of Immune System Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Tagcloud ?		1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally	19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 pla2g4c q13 radio srm zin
Tagcloud (Difference) ?		1beta autoinhibitory bm characterizes creating cytokines fanca fanconi hypersensitive inactivated leukemic loop mapkapk mononuclear multipotent overproduced overproduction p38 phagocytes posttranscriptionally potently progenitor progenitors progressive reasoning tlr toll transcriptionally	19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 pla2g4c q13 radio srm zin
Tagcloud (Intersection) ?