F2RL2 and JAM2

Number of citations of the paper that reports this interaction (PubMedID 17057644)
19

Data Source:
HPRD (in vitro, in vivo)

		F2RL2	JAM2
Description		coagulation factor II thrombin receptor like 2	junctional adhesion molecule 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Apical Plasma Membrane Protein-containing Complex	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Cell Surface Membrane Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Anchoring Junction Protein Complex Involved In Cell Adhesion
	Molecular Function	Proteinase-activated Receptor Activity Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity Receptor Ligand Activity	Integrin Binding Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Coagulation Hemostasis Response To Wounding Platelet Activation Positive Regulation Of Insulin Secretion Regulation Of Biological Quality Thrombin-activated Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway	Leukocyte Cell-cell Adhesion Spermatid Development Negative Regulation Of Myelination Maintenance Of Blood-brain Barrier Cellular Extravasation Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)	Cell surface interactions at the vascular wall Integrin cell surface interactions
Drugs
Diseases
GWAS		Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)	Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3	10 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 PICK1 SOX8 TDP2 TJP1 YBX1
Entrez ID		2151	58494
HPRD ID		03561	06041
Ensembl ID		ENSG00000164220	ENSG00000154721
Uniprot IDs		O00254	P57087
PDB IDs
Enriched GO Terms of Interacting Partners?		Maintenance Of Blood-brain Barrier Bicellular Tight Junction Cell-cell Junction Anchoring Junction Tight Junction Cell-cell Adhesion Anatomical Structure Homeostasis Tissue Homeostasis Regulation Of Platelet Activation Hematopoietic Stem Cell Migration To Bone Marrow Protein Complex Involved In Cell Adhesion Positive Regulation Of Establishment Of Endothelial Barrier Protein Localization To Bicellular Tight Junction Leukocyte Migration Platelet Activation Hematopoietic Stem Cell Migration Protein Localization To Cell Junction Neutrophil-mediated Killing Of Bacterium Thrombin-activated Receptor Signaling Pathway Positive Regulation Of Platelet Aggregation Cell-cell Junction Assembly Cell Adhesion Regulation Of Establishment Of Endothelial Barrier Cellular Extravasation Protein Localization To Cell-cell Junction Cell Migration Positive Regulation Of Homotypic Cell-cell Adhesion Integrin Binding Neutrophil Mediated Immunity Multicellular Organismal-level Homeostasis Cell-cell Contact Zone Cell-cell Junction Organization Cell Motility Regulation Of Cytoskeleton Organization Regulation Of Platelet Aggregation Killing By Host Of Symbiont Cells Cell-cell Adhesion Mediator Activity Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Biological Process Involved In Interaction With Symbiont Regulation Of Endothelial Cell Differentiation Homeostatic Process Bicellular Tight Junction Assembly Cell Junction Assembly Tight Junction Assembly Adherens Junction Organization Tight Junction Organization Leukocyte Cell-cell Adhesion Positive Regulation Of Calcium Ion Transmembrane Transport Biofilm Matrix Disassembly Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly	Mitochondrial Outer Membrane Fusion Maintenance Of Blood-brain Barrier Cell Development Adherens Junction Organization Tight Junction 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Cellular Component Maintenance Proteinase-activated Receptor Activity Regulation Of Biological Quality Thrombin-activated Receptor Activity Regulation Of Hormone Levels DTTP Biosynthetic Process Mitochondrion-mitochondrion Outer Membrane Tether Activity C5-methylcytidine-containing RNA Reader Activity TRNA Transport Single-stranded DNA Binding Histone Pre-mRNA 3'end Processing Complex MiRNA Transport CRD-mediated MRNA Stability Complex Protein Localization To Bicellular Tight Junction Negative Regulation Of Cytoskeleton Organization Cell-cell Junction Assembly Epithelial Cell Development Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Protein Localization To Cell Junction Positive Regulation Of Blood-brain Barrier Permeability Regulation Of Actin Filament-based Process Adherens Junction Maintenance Protein Localization To Adherens Junction Bicellular Tight Junction Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Photoreceptor Cell Differentiation Metanephric Tubule Formation Renal Vesicle Induction Metanephric Nephron Tubule Formation Astrocyte Fate Commitment Protein Complex Involved In Cell Adhesion Positive Regulation Of Monocyte Extravasation Negative Regulation Of Integrin Activation Hematopoietic Stem Cell Migration To Bone Marrow Negative Regulation Of Supramolecular Fiber Organization Regulation Of Insulin Secretion Pyrimidine Deoxyribonucleotide Biosynthetic Process Ameloblast Differentiation Ureter Morphogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?