JAM2 and NME3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		JAM2	NME3
Gene Name		junctional adhesion molecule 2	NME/NM23 nucleoside diphosphate kinase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Tight Junction	Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Heterodimerization Activity	Nucleoside Diphosphate Kinase Activity ATP Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Adhesion Blood Coagulation Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Leukocyte Migration	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process Nucleoside Triphosphate Biosynthetic Process Regulation Of Apoptotic Process
Pathways		Integrin cell surface interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		9 interactors: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1	8 interactors: APP HTR2A JAM2 NME1 NME2 SGTA UBQLN1 UBQLN4
Entrez ID		58494	4832
HPRD ID		06041	03488
Ensembl ID		ENSG00000154721	ENSG00000103024
Uniprot IDs		P57087	Q13232
PDB IDs			1ZS6
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Muscle Cell Differentiation Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Cell-cell Signaling Involved In Cell-cell Junction Organization In Utero Embryonic Development Retinal Rod Cell Differentiation Signaling Cell Communication Renal Vesicle Induction Astrocyte Fate Commitment Metanephric Nephron Tubule Formation Response To Magnetism Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Muscle Cell Differentiation CRD-mediated MRNA Stabilization Regulation Of Cellular Process Ureter Morphogenesis Metanephric Tubule Formation Establishment Of Endothelial Intestinal Barrier Chordate Embryonic Development Cellular Response To Stimulus Embryo Development Ending In Birth Or Egg Hatching Epithelial Cell Development Metanephric Nephron Tubule Morphogenesis Myeloid Progenitor Cell Differentiation	Nucleobase-containing Small Molecule Interconversion GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Cellular Chemical Homeostasis Phospholipase C-activating Serotonin Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Positive Regulation Of Epithelial Cell Proliferation Cellular Homeostasis Positive Regulation Of Phosphatidylinositol Biosynthetic Process Purine Nucleotide Biosynthetic Process Adult Behavior Ribose Phosphate Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Cell Proliferation Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Chemical Homeostasis Regulation Of Cellular Protein Metabolic Process Artery Smooth Muscle Contraction Purine Nucleoside Metabolic Process Tonic Smooth Muscle Contraction Neuron Remodeling Regulation Of Binding Learning Or Memory Urinary Bladder Smooth Muscle Contraction Peptidyl-histidine Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Proliferation Cognition Ribonucleotide Metabolic Process Nucleoside Metabolic Process Cellular Calcium Ion Homeostasis Nucleotide Biosynthetic Process Positive Regulation Of Glycolytic Process
Tagcloud ?		angptl4 api5 asap1 cebpb cpp ctbbd1 homer1 itgb6 letm1 methylphenidate mitochondrion nfkbia notch3 nsbp1 overrepresented pcdh10 per3 perp pfc prps18c reinforcer s100a9 shrs sik1 stimulant taf1 ube2d2 uqcrc2 usp27x	address affecting arhgdib autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 oncogene oncogenic proto rescued solid timp1 timp2 turnover
Tagcloud (Difference) ?		angptl4 api5 asap1 cebpb cpp ctbbd1 homer1 itgb6 letm1 methylphenidate mitochondrion nfkbia notch3 nsbp1 overrepresented pcdh10 per3 perp pfc prps18c reinforcer s100a9 shrs sik1 stimulant taf1 ube2d2 uqcrc2 usp27x	address affecting arhgdib autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 oncogene oncogenic proto rescued solid timp1 timp2 turnover
Tagcloud (Intersection) ?