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F2RL2 and F2RL3
Number of citations of the paper that reports this interaction (PMID
10766244
)
79
Data Source:
HPRD
(in vivo)
F2RL2
F2RL3
Gene Name
coagulation factor II (thrombin) receptor-like 2
coagulation factor II (thrombin) receptor-like 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
Apical Plasma Membrane
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Phosphatidylinositol Phospholipase C Activity
Protein Binding
Thrombin Receptor Activity
Thrombin Receptor Activity
Biological Process
Blood Coagulation
Metabolic Process
Response To Wounding
Platelet Activation
Thrombin Receptor Signaling Pathway
Signal Transduction
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Blood Coagulation
Response To Wounding
Platelet Activation
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Platelet Dense Granule Organization
Thrombin Receptor Signaling Pathway
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
Signaling by GPCR
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
G alpha (q) signalling events
Thrombin signalling through proteinase activated receptors (PARs)
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Platelet activation, signaling and aggregation
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
Signaling by GPCR
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
G alpha (q) signalling events
Thrombin signalling through proteinase activated receptors (PARs)
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
CDH5
CTSG
ECT2
F11R
F2
F2RL3
JAM2
JAM3
2 interactors:
F2
F2RL2
Entrez ID
2151
9002
HPRD ID
03561
04148
Ensembl ID
ENSG00000164220
Uniprot IDs
O00254
Q96RI0
PDB IDs
2ZPK
3QDZ
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Leukocyte Migration
Response To Wounding
Extracellular Matrix Organization
Extracellular Structure Organization
Response To Stress
Cell Junction Assembly
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cell-cell Junction Organization
Positive Regulation Of Intracellular Transport
Positive Regulation Of Calcium Ion Transport Into Cytosol
Cell Migration
Tight Junction Assembly
Cell Motility
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Response To Stimulus
Apical Junction Assembly
Immune System Process
Inflammatory Response
Regulation Of Calcium Ion Transport Into Cytosol
Regulation Of Intracellular Transport
Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion
Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Cell Adhesion
Positive Regulation Of Calcium Ion Transport
Locomotion
Regulation Of Cytoskeleton Organization
Defense Response
Neutrophil Mediated Killing Of Gram-positive Bacterium
Cell-cell Junction Assembly
Movement Of Cell Or Subcellular Component
Regulation Of Ion Homeostasis
Positive Regulation Of Transport
Regulation Of Blood Pressure
Cell Surface Receptor Signaling Pathway
Regulation Of Calcium Ion Transport
Platelet Activation
Positive Regulation Of Ion Transport
Establishment Of Endothelial Intestinal Barrier
Regulation Of Cellular Component Organization
Killing By Host Of Symbiont Cells
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Organelle Organization
Myeloid Progenitor Cell Differentiation
Signaling
Platelet Dense Granule Organization
Blood Vessel Maturation
Platelet Activation
Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Negative Regulation Of Fibrinolysis
Cell Activation
Response To Wounding
Thrombin Receptor Signaling Pathway
Peptidyl-glutamic Acid Carboxylation
Regulation Of Fibrinolysis
Blood Coagulation, Intrinsic Pathway
Negative Regulation Of Astrocyte Differentiation
Negative Regulation Of Platelet Activation
Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Collagen Biosynthetic Process
Positive Regulation Of Collagen Metabolic Process
Regulation Of Astrocyte Differentiation
Fibrinolysis
Regulation Of Platelet Activation
Positive Regulation Of Blood Coagulation
Negative Regulation Of Glial Cell Differentiation
Regulation Of Collagen Metabolic Process
Positive Regulation Of Calcium Ion Transport Into Cytosol
Acute-phase Response
Positive Regulation Of Coagulation
Positive Regulation Of Wound Healing
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Wound Healing
Acute Inflammatory Response
Regulation Of Glial Cell Differentiation
Regulation Of Calcium Ion Transport Into Cytosol
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Calcium Ion Transport
Regulation Of Blood Coagulation
Regulation Of Gliogenesis
Positive Regulation Of Cell Growth
Regulation Of Wound Healing
Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Cell Shape
Regulation Of Ion Homeostasis
Protein Activation Cascade
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Cytosolic Calcium Ion Homeostasis
Tagcloud
?
al7a1
arhgap1
c25h16orf71
conceptus
ddx58
degs
endometria
ensbtat00000050193
estrus
fbxl7
herc6
ifi16
ifnt
insemination
lims2
loc507810
mgc127874
mgc128929
parp12
rnaseq
rnf213
samd9
serbp1
srgap2
tbc1d1
wbscr17
znfx1
zswim4
zxfx1
Tagcloud (Difference)
?
al7a1
arhgap1
c25h16orf71
conceptus
ddx58
degs
endometria
ensbtat00000050193
estrus
fbxl7
herc6
ifi16
ifnt
insemination
lims2
loc507810
mgc127874
mgc128929
parp12
rnaseq
rnf213
samd9
serbp1
srgap2
tbc1d1
wbscr17
znfx1
zswim4
zxfx1
Tagcloud (Intersection)
?