JAM2 and YBX1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		JAM2	YBX1
Gene Name		junctional adhesion molecule 2	Y box binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Tight Junction	Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytoplasmic Stress Granule Ribonucleoprotein Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	Protein Binding Protein Heterodimerization Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Cell Adhesion Blood Coagulation Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Leukocyte Migration	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Splicing Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization
Pathways		Integrin cell surface interactions Cell surface interactions at the vascular wall	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		9 interactors: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1	41 interactors: ACTA2 AKT1 ANKRD2 APBB1 CALM1 CSNK2A1 CTCF FBXO33 FMR1 FUS GSK3B HABP4 HIST1H1C HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCP2 LSM3 MAPK1 NFYB PCBP2 PCNA PRPF40A PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 UBC VEGFA
Entrez ID		58494	4904
HPRD ID		06041	01095
Ensembl ID		ENSG00000154721	ENSG00000065978
Uniprot IDs		P57087	P67809
PDB IDs			1H95
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Muscle Cell Differentiation Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Cell-cell Signaling Involved In Cell-cell Junction Organization In Utero Embryonic Development Retinal Rod Cell Differentiation Signaling Cell Communication Renal Vesicle Induction Astrocyte Fate Commitment Metanephric Nephron Tubule Formation Response To Magnetism Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Muscle Cell Differentiation CRD-mediated MRNA Stabilization Regulation Of Cellular Process Ureter Morphogenesis Metanephric Tubule Formation Establishment Of Endothelial Intestinal Barrier Chordate Embryonic Development Cellular Response To Stimulus Embryo Development Ending In Birth Or Egg Hatching Epithelial Cell Development Metanephric Nephron Tubule Morphogenesis Myeloid Progenitor Cell Differentiation	Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Immune Response Immune Response Regulation Of Immune System Process Negative Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus Positive Regulation Of Metabolic Process Immune System Process Response To Stress Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Apoptotic Process Neurotrophin Signaling Pathway Innate Immune Response RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Growth Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Cell Activation Regulation Of Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Regulation Of Cell Differentiation System Development Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Translation Negative Regulation Of Biosynthetic Process Gene Expression Blood Coagulation Hemostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Wound Healing Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cell Growth Regulation Of RNA Metabolic Process Regulation Of Growth Posttranscriptional Regulation Of Gene Expression
Tagcloud ?		angptl4 api5 asap1 cebpb cpp ctbbd1 homer1 itgb6 letm1 methylphenidate mitochondrion nfkbia notch3 nsbp1 overrepresented pcdh10 per3 perp pfc prps18c reinforcer s100a9 shrs sik1 stimulant taf1 ube2d2 uqcrc2 usp27x	annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3
Tagcloud (Difference) ?		angptl4 api5 asap1 cebpb cpp ctbbd1 homer1 itgb6 letm1 methylphenidate mitochondrion nfkbia notch3 nsbp1 overrepresented pcdh10 per3 perp pfc prps18c reinforcer s100a9 shrs sik1 stimulant taf1 ube2d2 uqcrc2 usp27x	annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3
Tagcloud (Intersection) ?