JAM2 and JAM3

Number of citations of the paper that reports this interaction (PubMedID 11823489)
0

Data Source:
HPRD (in vitro, in vivo)

		JAM2	JAM3
Description		junctional adhesion molecule 2	junctional adhesion molecule 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Cell Surface Membrane Somatodendritic Compartment Cell-cell Contact Zone Tight Junction Anchoring Junction Protein Complex Involved In Cell Adhesion	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Microvillus Cell-cell Junction Bicellular Tight Junction Membrane Desmosome Filamentous Actin Paranodal Junction Schmidt-Lanterman Incisure Cell-cell Contact Zone Tight Junction Anchoring Junction Protein Complex Involved In Cell Adhesion
	Molecular Function	Integrin Binding Protein Binding	Integrin Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell-cell Adhesion Mediator Activity
	Biological Process	Leukocyte Cell-cell Adhesion Spermatid Development Negative Regulation Of Myelination Maintenance Of Blood-brain Barrier Cellular Extravasation Leukocyte Tethering Or Rolling Lymphocyte Aggregation Hematopoietic Stem Cell Migration To Bone Marrow Cell-cell Adhesion Positive Regulation Of Lymphocyte Migration	Angiogenesis Neutrophil Homeostasis Adaptive Immune Response Myeloid Progenitor Cell Differentiation Leukocyte Migration Involved In Inflammatory Response Cell Adhesion Cell-matrix Adhesion Spermatogenesis Spermatid Development Cell Migration Transmission Of Nerve Impulse Establishment Of Cell Polarity Cell Differentiation Negative Regulation Of Integrin Activation Negative Regulation Of Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Adherens Junction Assembly Protein Localization To Cell Surface Maintenance Of Blood-brain Barrier Myelination Apical Protein Localization System Development Leukocyte Migration Regulation Of Neutrophil Chemotaxis Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Hematopoietic Stem Cell Migration To Bone Marrow Granulocyte Migration Cell-cell Adhesion Protein Localization To Cell Junction Positive Regulation Of Membrane Permeability Positive Regulation Of Monocyte Extravasation
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions	Cell surface interactions at the vascular wall Integrin cell surface interactions
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Cognitive performance ( 19734545) Longitudinal change in brain amyloid plaque burden ( 26268530) Metabolite levels ( 23823483)	Blood protein levels ( 30072576) Neutrophil count ( 32888494)
Interacting Genes		10 interacting genes: CSNK1A1L F2RL2 GPR20 JAM3 NME3 PICK1 SOX8 TDP2 TJP1 YBX1	8 interacting genes: F2RL2 ITGAM ITGAX JAM2 MEOX2 PICK1 RHOU TJP1
Entrez ID		58494	83700
HPRD ID		06041	06042
Ensembl ID		ENSG00000154721	ENSG00000166086
Uniprot IDs		P57087	Q9BX67
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Outer Membrane Fusion Maintenance Of Blood-brain Barrier Cell Development Adherens Junction Organization Tight Junction 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Cellular Component Maintenance Proteinase-activated Receptor Activity Regulation Of Biological Quality Thrombin-activated Receptor Activity Regulation Of Hormone Levels DTTP Biosynthetic Process Mitochondrion-mitochondrion Outer Membrane Tether Activity C5-methylcytidine-containing RNA Reader Activity TRNA Transport Single-stranded DNA Binding Histone Pre-mRNA 3'end Processing Complex MiRNA Transport CRD-mediated MRNA Stability Complex Protein Localization To Bicellular Tight Junction Negative Regulation Of Cytoskeleton Organization Cell-cell Junction Assembly Epithelial Cell Development Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Protein Localization To Cell Junction Positive Regulation Of Blood-brain Barrier Permeability Regulation Of Actin Filament-based Process Adherens Junction Maintenance Protein Localization To Adherens Junction Bicellular Tight Junction Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Photoreceptor Cell Differentiation Metanephric Tubule Formation Renal Vesicle Induction Metanephric Nephron Tubule Formation Astrocyte Fate Commitment Protein Complex Involved In Cell Adhesion Positive Regulation Of Monocyte Extravasation Negative Regulation Of Integrin Activation Hematopoietic Stem Cell Migration To Bone Marrow Negative Regulation Of Supramolecular Fiber Organization Regulation Of Insulin Secretion Pyrimidine Deoxyribonucleotide Biosynthetic Process Ameloblast Differentiation Ureter Morphogenesis	Regulation Of Establishment Of Protein Localization Cell-cell Adhesion Integrin Binding Integrin Complex Heterotypic Cell-cell Adhesion Maintenance Of Blood-brain Barrier Tight Junction Podosome Regulation Of Myelination Positive Regulation Of Establishment Of Protein Localization Cell Adhesion Tertiary Granule Membrane Regulation Of Protein Localization Cellular Component Maintenance Plasma Membrane Regulation Of Cell Migration Anchoring Junction Proteinase-activated Receptor Activity Integrin AlphaM-beta2 Complex Integrin-mediated Signaling Pathway Regulation Of Cell Motility Integrin AlphaX-beta2 Complex Regulation Of Locomotion Positive Regulation Of Endothelial Tube Morphogenesis Cell-matrix Adhesion Regulation Of Secretion By Cell Thrombin-activated Receptor Activity Regulation Of Secretion Negative Regulation Of Dopamine Metabolic Process Positive Regulation Of Microglial Cell Mediated Cytotoxicity Positive Regulation Of Neutrophil Degranulation Response To Curcumin Complement-mediated Synapse Pruning Negative Regulation Of Catecholamine Metabolic Process Vertebrate Eye-specific Patterning Cell-substrate Adhesion Ectodermal Cell Differentiation Positive Regulation Of Locomotion Positive Regulation Of Cell Migration Regulation Of Nervous System Process Positive Regulation Of Cell Motility Somite Specification Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Positive Regulation Of Blood-brain Barrier Permeability Protein Localization To Adherens Junction Bicellular Tight Junction Membrane Curvature Sensor Activity Hematopoietic Stem Cell Migration To Bone Marrow Protein Complex Involved In Cell Adhesion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?