JAM2 and JAM3

Number of citations of the paper that reports this interaction (PMID 11823489)
20

Data Source:
HPRD (in vitro, in vivo)

		JAM2	JAM3
Gene Name		junctional adhesion molecule 2	junctional adhesion molecule 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Tight Junction	Extracellular Space Golgi Apparatus Plasma Membrane Tight Junction Integral Component Of Membrane Desmosome Paranodal Junction Schmidt-Lanterman Incisure Cell-cell Contact Zone
	Molecular Function	Protein Binding Protein Heterodimerization Activity	Integrin Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Cell Adhesion Blood Coagulation Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Leukocyte Migration	Angiogenesis Neutrophil Homeostasis Adaptive Immune Response Myeloid Progenitor Cell Differentiation Leukocyte Migration Involved In Inflammatory Response Cell-matrix Adhesion Spermatid Development Blood Coagulation Transmission Of Nerve Impulse Establishment Of Cell Polarity Extracellular Matrix Organization Axon Regeneration Myelination Leukocyte Migration Regulation Of Neutrophil Chemotaxis Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion
Pathways		Integrin cell surface interactions Cell surface interactions at the vascular wall	Integrin cell surface interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Cognitive performance ( 19734545)
Protein-Protein Interactions		9 interactors: CSNK1A1L F2RL2 GPR20 JAM3 NME3 SOX8 TDP2 TJP1 YBX1	6 interactors: F2RL2 ITGAM ITGAX JAM2 PICK1 TJP1
Entrez ID		58494	83700
HPRD ID		06041	06042
Ensembl ID		ENSG00000154721	ENSG00000166086
Uniprot IDs		P57087	Q9BX67
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Muscle Cell Differentiation Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Cell-cell Signaling Involved In Cell-cell Junction Organization In Utero Embryonic Development Retinal Rod Cell Differentiation Signaling Cell Communication Renal Vesicle Induction Astrocyte Fate Commitment Metanephric Nephron Tubule Formation Response To Magnetism Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Muscle Cell Differentiation CRD-mediated MRNA Stabilization Regulation Of Cellular Process Ureter Morphogenesis Metanephric Tubule Formation Establishment Of Endothelial Intestinal Barrier Chordate Embryonic Development Cellular Response To Stimulus Embryo Development Ending In Birth Or Egg Hatching Epithelial Cell Development Metanephric Nephron Tubule Morphogenesis Myeloid Progenitor Cell Differentiation	Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Leukocyte Migration Extracellular Matrix Organization Extracellular Structure Organization Single Organismal Cell-cell Adhesion Cell-cell Signaling Involved In Cell-cell Junction Organization Glial Cell Development Response To Stress Integrin-mediated Signaling Pathway Response To External Stimulus Microglia Development Cell Migration Glial Cell Differentiation Response To Magnetism Cell Motility Ectodermal Cell Differentiation Gliogenesis Establishment Of Endothelial Intestinal Barrier Response To Stimulus DNA Methylation Involved In Embryo Development Cell Adhesion Dendritic Spine Maintenance Signal Transduction Locomotion Neuronal Ion Channel Clustering Thrombin Receptor Signaling Pathway Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Vascular Permeability Negative Regulation Of Actin Nucleation Cell Surface Receptor Signaling Pathway Signaling Cell Communication Movement Of Cell Or Subcellular Component Long Term Synaptic Depression Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Receptor Internalization Macrophage Differentiation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendritic Spine Organization Heterotypic Cell-cell Adhesion DNA Methylation Involved In Gamete Generation Regulation Of Actin Nucleation Ectoderm Development Cellular Response To Glucose Starvation Monoamine Transport Cellular Component Maintenance
Tagcloud ?		angptl4 api5 asap1 cebpb cpp ctbbd1 homer1 itgb6 letm1 methylphenidate mitochondrion nfkbia notch3 nsbp1 overrepresented pcdh10 per3 perp pfc prps18c reinforcer s100a9 shrs sik1 stimulant taf1 ube2d2 uqcrc2 usp27x
Tagcloud (Difference) ?		angptl4 api5 asap1 cebpb cpp ctbbd1 homer1 itgb6 letm1 methylphenidate mitochondrion nfkbia notch3 nsbp1 overrepresented pcdh10 per3 perp pfc prps18c reinforcer s100a9 shrs sik1 stimulant taf1 ube2d2 uqcrc2 usp27x
Tagcloud (Intersection) ?