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F2RL2
Gene Name
coagulation factor II (thrombin) receptor-like 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
Apical Plasma Membrane
Molecular Function
Phosphatidylinositol Phospholipase C Activity
Protein Binding
Thrombin Receptor Activity
Biological Process
Blood Coagulation
Metabolic Process
Response To Wounding
Platelet Activation
Thrombin Receptor Signaling Pathway
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
Signaling by GPCR
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
G alpha (q) signalling events
Thrombin signalling through proteinase activated receptors (PARs)
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-protein Interactions
8 interactors:
CDH5
CTSG
ECT2
F11R
F2
F2RL3
JAM2
JAM3
Entrez ID
2151
HPRD ID
03561
Ensembl ID
ENSG00000164220
Uniprot IDs
O00254
PDB IDs
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Leukocyte Migration
Response To Wounding
Extracellular Matrix Organization
Extracellular Structure Organization
Response To Stress
Cell Junction Assembly
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cell-cell Junction Organization
Positive Regulation Of Intracellular Transport
Positive Regulation Of Calcium Ion Transport Into Cytosol
Cell Migration
Tight Junction Assembly
Cell Motility
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Response To Stimulus
Apical Junction Assembly
Immune System Process
Inflammatory Response
Regulation Of Calcium Ion Transport Into Cytosol
Regulation Of Intracellular Transport
Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion
Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Cell Adhesion
Positive Regulation Of Calcium Ion Transport
Locomotion
Regulation Of Cytoskeleton Organization
Defense Response
Neutrophil Mediated Killing Of Gram-positive Bacterium
Cell-cell Junction Assembly
Movement Of Cell Or Subcellular Component
Regulation Of Ion Homeostasis
Positive Regulation Of Transport
Regulation Of Blood Pressure
Cell Surface Receptor Signaling Pathway
Regulation Of Calcium Ion Transport
Platelet Activation
Positive Regulation Of Ion Transport
Establishment Of Endothelial Intestinal Barrier
Regulation Of Cellular Component Organization
Killing By Host Of Symbiont Cells
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Organelle Organization
Myeloid Progenitor Cell Differentiation
Signaling
Platelet Dense Granule Organization
Blood Vessel Maturation
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