EVPL and PLEKHA5

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		EVPL	PLEKHA5
Gene Name		envoplakin	pleckstrin homology domain containing, family A member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytoskeleton Desmosome Extracellular Vesicular Exosome	Cytosol Membrane
	Molecular Function	Structural Molecule Activity Protein Binding, Bridging	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Keratinization	Biological_process Reproductive System Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LOR PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	30 interactors: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 UPF1 WASH2P YWHAG
Entrez ID		2125	54477
HPRD ID		03352	09684
Ensembl ID		ENSG00000167880	ENSG00000052126
Uniprot IDs		K7EKI0 Q92817	Q9HAU0
PDB IDs			2DKP
Enriched GO Terms of Interacting Partners?		Keratinocyte Differentiation Skin Development Epidermal Cell Differentiation Epidermis Development Keratinization Epithelial Cell Differentiation Epithelium Development Peptide Cross-linking Tissue Development Anatomical Structure Development Organ Development System Development Developmental Process Multicellular Organismal Development Cell Differentiation Keratinocyte Activation Ventricular Compact Myocardium Morphogenesis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Keratinocyte Migration Complement Activation, Lectin Pathway Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Cell Junction Hemidesmosome Assembly Desmosome Organization Keratinocyte Proliferation	Apoptotic Process Programmed Cell Death Cell Death Death Hemidesmosome Assembly Glomerular Visceral Epithelial Cell Differentiation Regulation Of Protein Complex Disassembly Cellular Localization Regulation Of Cellular Component Organization Movement Of Cell Or Subcellular Component Cellular Process Retina Development In Camera-type Eye Organelle Organization Generation Of Neurons Cell Differentiation Involved In Kidney Development Neuron Differentiation Cytoskeleton Organization Regulation Of Actin Filament Polymerization Microtubule-based Process Neurogenesis Metanephric Glomerular Basement Membrane Development Axon Extension Involved In Regeneration Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cell-substrate Junction Assembly Actin Filament Capping Membrane Organization Regulation Of Cytoskeleton Organization Glomerulus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Depolymerization Epithelial Cell Differentiation Regulation Of Organelle Organization Metanephric Glomerular Visceral Epithelial Cell Development Response To Axon Injury Protein Localization Neuron Development Regulation Of Actin Filament Depolymerization Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Polymerization Sensory Organ Development Glomerular Parietal Epithelial Cell Differentiation Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Centriole-centriole Cohesion Response To Insulin Establishment Of Localization In Cell Microtubule-based Movement Intracellular Transport Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport
Tagcloud ?		aeruginosa arise cf cheats chronically costly ethical governing grow homoserine hosts hsl lactone lasr live mammal mimics oxo polymicrobial pseudomonas qs quantifying quorum recapitulate repeatedly run spatially specialized virulence	a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul
Tagcloud (Difference) ?		aeruginosa arise cf cheats chronically costly ethical governing grow homoserine hosts hsl lactone lasr live mammal mimics oxo polymicrobial pseudomonas qs quantifying quorum recapitulate repeatedly run spatially specialized virulence	a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul
Tagcloud (Intersection) ?