EVPL and IVL

Number of citations of the paper that reports this interaction (PubMedID 8999895)
0

Data Source:
HPRD (in vivo)

		EVPL	IVL
Description		envoplakin	involucrin
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytosol Cytoskeleton Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome Anchoring Junction	Cornified Envelope Cytoplasm Centrosome Cytosol Nuclear Body Extracellular Exosome
	Molecular Function	Structural Molecule Activity Cadherin Binding	Protein Binding
	Biological Process	Regulation Of Antibacterial Peptide Production Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Keratinization Wound Healing Intermediate Filament Cytoskeleton Organization	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization
Pathways		Formation of the cornified envelope	Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)	Asthma ( 31619474) Vitamin D levels ( 26704534)
Interacting Genes		14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	10 interacting genes: ACD CRK CSTA DSP EVPL KRT1 LORICRIN POT1 SPRR3 UCHL5
Entrez ID		2125	3713
HPRD ID		03352	00931
Ensembl ID		ENSG00000167880	ENSG00000163207
Uniprot IDs		B7ZLH8 K7EKI0 Q92817	P07476
PDB IDs		4QMD
Enriched GO Terms of Interacting Partners?		Cornified Envelope Peptide Cross-linking Keratinization Structural Constituent Of Skin Epidermis Keratinocyte Differentiation Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Epidermal Cell Differentiation Intermediate Filament Intermediate Filament Organization Structural Constituent Of Cytoskeleton Epidermis Development Epithelial Cell Differentiation Keratin Filament Cytoskeleton Organization Protein Modification Process Structural Molecule Activity Wound Healing Supramolecular Fiber Organization Cytosol Extracellular Exosome Protein Heterotetramerization Tissue Development Protein Heterooligomerization Desmosome Positive Regulation Of Epidermis Development Response To Wounding Endopeptidase Inhibitor Activity Cytoplasm Protein Metabolic Process Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Intermediate Filament Polymerization Humoral Immune Response Antibacterial Humoral Response Regulation Of Epidermis Development Developmental Process Scaffold Protein Binding Keratinocyte Activation Intermediate Filament Polymerization Or Depolymerization Copulation Organelle Organization Protein Tetramerization Peptidase Inhibitor Complex Peptidase Inhibitor Activity Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication Cellular Developmental Process Extracellular Space Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Keratinocyte Migration Cardiac Muscle Cell-cardiac Muscle Cell Adhesion	Peptide Cross-linking Cornified Envelope Keratinocyte Differentiation Epidermal Cell Differentiation Keratinization Epidermis Development Telomere Assembly Epithelial Cell Differentiation Shelterin Complex Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Maintenance Nuclear Telomere Cap Complex Wound Healing Telomere Capping Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Telomere Maintenance Regulation Of DNA Strand Elongation Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Organelle Organization Telomere Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Developmental Process Intermediate Filament Desmosome Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Structural Molecule Activity Response To Stress Negative Regulation Of Telomere Maintenance Cytoskeleton Organization Response To Wounding Protein Modification Process Regulation Of Telomere Maintenance Via Telomerase Endopeptidase Inhibitor Activity Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomere Lengthening Ciliary Neurotrophic Factor Binding Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Structural Constituent Of Skin Epidermis Positive Regulation Of DNA Metabolic Process Macromolecule Metabolic Process
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