EVPL and DSP

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
HPRD (in vivo)

		EVPL	DSP
Gene Name		envoplakin	desmoplakin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytoskeleton Desmosome Extracellular Vesicular Exosome	Cornified Envelope Nucleus Mitochondrion Intermediate Filament Plasma Membrane Fascia Adherens Intercalated Disc Basolateral Plasma Membrane Desmosome Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding, Bridging	Protein Kinase C Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Protein Binding, Bridging Poly(A) RNA Binding Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Keratinization	Desmosome Organization Ventricular Compact Myocardium Morphogenesis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epidermis Development Single Organismal Cell-cell Adhesion Peptide Cross-linking Keratinocyte Differentiation Adherens Junction Organization Wound Healing Intermediate Filament Organization Protein Localization To Adherens Junction Ventricular Cardiac Muscle Cell Action Potential Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Rate By Cardiac Conduction
Pathways			Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Interstitial lung disease ( 23583980)
Protein-Protein Interactions		14 interactors: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LOR PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	28 interactors: ARID3A CASP10 CASP2 CASP4 CASP6 CASP7 CASP9 CDH5 COL17A1 CSTA DES DSC1 EVPL IVL JUP KRT1 KRT5 KRT6A PECAM1 PKP1 PKP2 PKP3 PKP4 PRKACA PRKCE PSEN1 UCHL5 VIM
Entrez ID		2125	1832
HPRD ID		03352	00513
Ensembl ID		ENSG00000167880	ENSG00000096696
Uniprot IDs		K7EKI0 Q92817	D7RX09 P15924
PDB IDs			1LM5 1LM7 3R6N
Enriched GO Terms of Interacting Partners?		Keratinocyte Differentiation Skin Development Epidermal Cell Differentiation Epidermis Development Keratinization Epithelial Cell Differentiation Epithelium Development Peptide Cross-linking Tissue Development Anatomical Structure Development Organ Development System Development Developmental Process Multicellular Organismal Development Cell Differentiation Keratinocyte Activation Ventricular Compact Myocardium Morphogenesis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Keratinocyte Migration Complement Activation, Lectin Pathway Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Cell Junction Hemidesmosome Assembly Desmosome Organization Keratinocyte Proliferation	Desmosome Assembly Cell Junction Assembly Desmosome Organization Cell Adhesion Execution Phase Of Apoptosis Apoptotic Process Programmed Cell Death Cell Death Death Epithelium Development Tissue Development Developmental Process Anatomical Structure Development Cell-cell Junction Organization Skin Development Cell-cell Junction Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intermediate Filament Organization Single Organismal Cell-cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Proteolysis Organ Development Epidermis Development Multicellular Organismal Development System Development Intermediate Filament Cytoskeleton Organization Intermediate Filament Bundle Assembly Intermediate Filament-based Process Cardiac Conduction Peptide Cross-linking Cellular Component Assembly Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Contraction Apoptotic Signaling Pathway Regulation Of Tight Junction Assembly Intrinsic Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Peptidase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Hemidesmosome Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cell Cycle Process Signaling Neurotrophin Signaling Pathway Cell Communication By Electrical Coupling
Tagcloud ?		aeruginosa arise cf cheats chronically costly ethical governing grow homoserine hosts hsl lactone lasr live mammal mimics oxo polymicrobial pseudomonas qs quantifying quorum recapitulate repeatedly run spatially specialized virulence	aspirated cam5 cleaner dsus gcdfp ham56 hmb45 ipx k903 l26 mac387 mcea mcead14 nonneoplastic opd papanicolaou pcea plap processor scant scraped semiquantitatively slides thinprep tlp tlus tpp uchl unstained
Tagcloud (Difference) ?		aeruginosa arise cf cheats chronically costly ethical governing grow homoserine hosts hsl lactone lasr live mammal mimics oxo polymicrobial pseudomonas qs quantifying quorum recapitulate repeatedly run spatially specialized virulence	aspirated cam5 cleaner dsus gcdfp ham56 hmb45 ipx k903 l26 mac387 mcea mcead14 nonneoplastic opd papanicolaou pcea plap processor scant scraped semiquantitatively slides thinprep tlp tlus tpp uchl unstained
Tagcloud (Intersection) ?