EVPL and KRT5

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
HPRD (in vivo)

		EVPL	KRT5
Gene Name		envoplakin	keratin 5, type II
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Cytoplasm Cytoskeleton Desmosome Extracellular Vesicular Exosome	Nucleus Cytoplasm Mitochondrion Cytosol Intermediate Filament Plasma Membrane Membrane Keratin Filament Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding, Bridging	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Keratinization	Epidermis Development Hemidesmosome Assembly Cell Junction Assembly
Pathways			Cell junction organization Type I hemidesmosome assembly
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LOR PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3	19 interactors: ALOX12 ALOX12B APC DSP DST EVPL KIFC3 KRT1 KRT14 KRT15 KRT18 KRT31 KRT38 KRT40 PKP2 SUMO1 SUMO2 SUMO3 TCHP
Entrez ID		2125	3852
HPRD ID		03352	01010
Ensembl ID		ENSG00000167880	ENSG00000186081
Uniprot IDs		K7EKI0 Q92817	P13647
PDB IDs			3TNU
Enriched GO Terms of Interacting Partners?		Keratinocyte Differentiation Skin Development Epidermal Cell Differentiation Epidermis Development Keratinization Epithelial Cell Differentiation Epithelium Development Peptide Cross-linking Tissue Development Anatomical Structure Development Organ Development System Development Developmental Process Multicellular Organismal Development Cell Differentiation Keratinocyte Activation Ventricular Compact Myocardium Morphogenesis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Keratinocyte Migration Complement Activation, Lectin Pathway Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Cell Junction Hemidesmosome Assembly Desmosome Organization Keratinocyte Proliferation	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Skin Development Epidermis Development Establishment Of Skin Barrier Intermediate Filament Organization Regulation Of Water Loss Via Skin Protein Sumoylation Multicellular Organismal Water Homeostasis Hepoxilin Metabolic Process Hepoxilin Biosynthetic Process Intermediate Filament Bundle Assembly Cell Junction Assembly Water Homeostasis Bundle Of His Cell To Purkinje Myocyte Communication Anatomical Structure Development Cell-cell Junction Organization Positive Regulation Of Protein Catabolic Process Linoleic Acid Metabolic Process Desmosome Organization Hemidesmosome Assembly Lipoxygenase Pathway Developmental Process Positive Regulation Of Proteolysis Epithelium Development Long-chain Fatty Acid Biosynthetic Process Regulation Of Proteolysis Cytoskeleton Organization Ventricular Cardiac Muscle Cell Action Potential Tissue Development Regulation Of Heart Rate By Cardiac Conduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cellular Component Maintenance Positive Regulation Of Cellular Protein Catabolic Process Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Proteasomal Protein Catabolic Process Post-translational Protein Modification Single Organismal Cell-cell Adhesion Apoptotic Process Regulation Of Cardiac Muscle Cell Contraction Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Conduction Peptide Cross-linking Programmed Cell Death Cell-substrate Junction Assembly Cell Death Death
Tagcloud ?		aeruginosa arise cf cheats chronically costly ethical governing grow homoserine hosts hsl lactone lasr live mammal mimics oxo polymicrobial pseudomonas qs quantifying quorum recapitulate repeatedly run spatially specialized virulence	aldh1 ciliated columnar exposes foxj1 gynaecological hgsc hgscs krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Difference) ?		aeruginosa arise cf cheats chronically costly ethical governing grow homoserine hosts hsl lactone lasr live mammal mimics oxo polymicrobial pseudomonas qs quantifying quorum recapitulate repeatedly run spatially specialized virulence	aldh1 ciliated columnar exposes foxj1 gynaecological hgsc hgscs krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Intersection) ?