MECOM and HDAC4

  • Number of citations of the paper that reports this interaction (PMID 11568182)
  • 17
  • Data Source:
  • HPRD (in vitro, in vivo)

MECOM

HDAC4

Gene Name MDS1 and EVI1 complex locus histone deacetylase 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Male-pattern baldness ( 22693459)
  • Pulmonary function ( 21946350)
  • Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions 13 interactors: CREBBP CTBP1 CTBP2 HDAC1 HDAC4 KAT2B MBD3 PRMT1 SMAD1 SMAD2 SMAD3 SMAD4 SUMO1 89 interactors: ACTA1 ANKRA2 ANKRD11 APP AR ATF3 ATRX BCL6 BCOR BRMS1 CACNA1C CAMK2D CAMK4 CBX5 CCDC136 CDKN1A CDR2 CEBPD CIITA CSRP3 CTBP1 EFEMP2 ESR1 GATA1 GCM1 GNB1 GOLGA2 GSK3B HDAC3 HDAC7 HDAC9 HNF4A IFRD1 IKZF2 JDP2 KRT31 KRT38 KRT40 LCOR LDOC1 LZTR1 MAP1S MAPK1 MAPK3 MECOM MEF2A MEF2B MEF2C MEF2D MEGF10 MIF4GD MTUS2 NACC1 NCOR2 NFKB2 NFKBIE NPPB NR1H2 NR2C1 NR2C2 NUP155 PNMA1 PPARD PPARG PPP2R4 RANBP2 RARA RBBP4 REV3L RFXANK RINT1 RUNX2 RUNX3 RUVBL2 RXRA SMAD3 SRF SS18L1 SUMO1 SUMO2 SYK TNFRSF14 UBE2I YWHAE YWHAG YWHAQ YWHAZ ZBTB16 ZNF354A
Entrez ID 2122 9759
HPRD ID 01310 05610
Ensembl ID ENSG00000085276 ENSG00000068024
Uniprot IDs C7FEN9 E7EQ57 Q03112 Q13465 B7Z8G5 P56524 Q86YH7
PDB IDs 2H8N 2O94 2VQJ 2VQM 2VQO 2VQQ 2VQV 2VQW 3UXG 3UZD 3V31
Enriched GO Terms of Interacting Partners?
Tagcloud ?
admitted  aggressive  aml  april  attributed  august  d816v  documentation  eosinophilia  homogeneous  hypothesized  infarction  initially  kit  ldh  leukemic  man  minor  myeloproliferative  myocardial  neoplasm  novo  occurrence  persisting  runx1  splenomegaly  thalassemia  unrecognized  v617f 
300mg  50mg  ameliorated  ameliorates  ctgf  dawley  deacetylases  dn  emphasize  fibrogenesis  fibronectin  fibrosis  fibrotic  hdacs  histology  icam  microscope  migraine  myofibroblast  nephropathy  profibrotic  renoprotective  route  sma  sprague  stz  valproic  vpa 
Tagcloud (Difference) ?
admitted  aggressive  aml  april  attributed  august  d816v  documentation  eosinophilia  homogeneous  hypothesized  infarction  initially  kit  ldh  leukemic  man  minor  myeloproliferative  myocardial  neoplasm  novo  occurrence  persisting  runx1  splenomegaly  thalassemia  unrecognized  v617f 
300mg  50mg  ameliorated  ameliorates  ctgf  dawley  deacetylases  dn  emphasize  fibrogenesis  fibronectin  fibrosis  fibrotic  hdacs  histology  icam  microscope  migraine  myofibroblast  nephropathy  profibrotic  renoprotective  route  sma  sprague  stz  valproic  vpa 
Tagcloud (Intersection) ?