HDAC4 and NCOR2

  • Number of citations of the paper that reports this interaction (PMID 11804585)
  • 159
  • Data Source:
  • HPRD (in vitro)

HDAC4

NCOR2

Gene Name histone deacetylase 4 nuclear receptor corepressor 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Male-pattern baldness ( 22693459)
  • Pulmonary function ( 21946350)
  • Pulmonary function (interaction) ( 23284291)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) ( 23648065)
  • Cognitive performance ( 19734545)
Protein-Protein Interactions 89 interactors: ACTA1 ANKRA2 ANKRD11 APP AR ATF3 ATRX BCL6 BCOR BRMS1 CACNA1C CAMK2D CAMK4 CBX5 CCDC136 CDKN1A CDR2 CEBPD CIITA CSRP3 CTBP1 EFEMP2 ESR1 GATA1 GCM1 GNB1 GOLGA2 GSK3B HDAC3 HDAC7 HDAC9 HNF4A IFRD1 IKZF2 JDP2 KRT31 KRT38 KRT40 LCOR LDOC1 LZTR1 MAP1S MAPK1 MAPK3 MECOM MEF2A MEF2B MEF2C MEF2D MEGF10 MIF4GD MTUS2 NACC1 NCOR2 NFKB2 NFKBIE NPPB NR1H2 NR2C1 NR2C2 NUP155 PNMA1 PPARD PPARG PPP2R4 RANBP2 RARA RBBP4 REV3L RFXANK RINT1 RUNX2 RUNX3 RUVBL2 RXRA SMAD3 SRF SS18L1 SUMO1 SUMO2 SYK TNFRSF14 UBE2I YWHAE YWHAG YWHAQ YWHAZ ZBTB16 ZNF354A 84 interactors: AHR AKT1 AP2M1 AR ARNT ATXN1 ATXN1L BCL6 C1D CBFA2T2 CEBPB CEP63 CHUK CIR1 CNOT2 DDX20 E2F1 ESR1 ESR2 FOS FOXP1 HDAC1 HDAC10 HDAC3 HDAC4 HDAC5 HDAC7 HIST1H4A HNF4A INPP5K IRF5 JUN MYBL2 MYOD1 NCOA3 NCOA6 NCOR1 NFE2L2 NFKB1 NFKBIA NFKBIB NFKBIE NR1D1 NR1H2 NR1H4 NR1I2 NR2F1 NR2F2 NR3C1 NR4A1 PML POU2F1 PPARA PPARD PPARG RANBP9 RARA RARB RARG RBPJ RELA RUNX1 RUNX1T1 RXRA RXRG SAP30 SIN3A SKIL SNW1 SP1 SPEN SRF STAT5A STAT5B SUMO1 TBL1X THRA THRB TNIK TNIP2 UBE2I VDR YWHAE ZBTB16
Entrez ID 9759 9612
HPRD ID 05610 02910
Ensembl ID ENSG00000068024 ENSG00000196498
Uniprot IDs B7Z8G5 P56524 Q86YH7 C9J0Q5 C9JE98 C9JFD3 Q9Y618
PDB IDs 2H8N 2O94 2VQJ 2VQM 2VQO 2VQQ 2VQV 2VQW 3UXG 3UZD 3V31 1KKQ 1R2B 1XC5 2GPV 2L5G 2LTP 2ODD 3R29 3R2A 4A69
Enriched GO Terms of Interacting Partners?
Tagcloud ?
300mg  50mg  ameliorated  ameliorates  ctgf  dawley  deacetylases  dn  emphasize  fibrogenesis  fibronectin  fibrosis  fibrotic  hdacs  histology  icam  microscope  migraine  myofibroblast  nephropathy  profibrotic  renoprotective  route  sma  sprague  stz  valproic  vpa 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Difference) ?
300mg  50mg  ameliorated  ameliorates  ctgf  dawley  deacetylases  dn  emphasize  fibrogenesis  fibronectin  fibrosis  fibrotic  hdacs  histology  icam  microscope  migraine  myofibroblast  nephropathy  profibrotic  renoprotective  route  sma  sprague  stz  valproic  vpa 
amico  atm  dissect  entered  erg  formalin  fusions  hiseq  illumina  map2k5  maximise  mek5  men1  nbpf10  needle  ngs  opening  pik3cb  qiagen  read  routinely  screen  sections  spop  technologies  templates  tmprrs2  unstained  yielded 
Tagcloud (Intersection) ?