ESR1 and CDKN1A

  • Number of citations of the paper that reports this interaction (PMID 17911387)
  • 3
  • Data Source:
  • HPRD (in vitro)

ESR1

CDKN1A

Gene Name estrogen receptor 1 cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 266 interactors: ACTN4 AHR AKAP13 AKT1 AKT2 AR ARHGEF15 ARNT ATAD2 BAG1 BCAR1 BCAS2 BDNF BRCA1 BTF3 CALM1 CALM2 CALM3 CAV1 CBLL1 CCNC CCND1 CCNH CCNT1 CDC25B CDK2 CDK7 CDK8 CDKN1A CEBPA CEBPB CHD9 CHUK CITED1 COPS5 CREBBP CSNK2B CTNNB1 CUEDC2 CUL4B DAP3 DDX5 DDX54 DNTTIP2 DUT EGFR EHMT2 EIF3I EP300 ERBB2 ESR2 ESRRA FHL2 FKBP4 FKBP5 FLII FOXO1 FOXO3 FOXO4 GADD45B GADD45G GNAI1 GNAI2 GNAI3 GRB2 GRIP1 GTF2B GTF2H1 HDAC4 HDAC5 HDAC9 HEXIM1 HNF4A HSP90AA1 HSP90AB1 HSPA4 HSPA8 IGF1R ING1 ISL1 ITGB3BP JUN JUNB JUND KAT5 KDM5A KIF1A KLF5 KMT2D LCK LCOR LDB1 LINC00312 LRIF1 MAPK1 MAPK14 MAPK3 MDM2 MED1 MED10 MED12 MED13 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED25 MED6 MED7 MEN1 MGMT MKNK2 MMS19 MNAT1 MPG MSH2 MTA1 MTA2 MTA3 MTCH2 MUC1 MVP NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOA7 NCOR1 NCOR2 NELFB NFKB1 NPPA NR0B1 NR0B2 NR1H4 NR2C1 NR2C2 NR2F1 NR2F6 NRIP1 NSD1 OTUB1 PAGR1 PAK1 PAK6 PELP1 PGC PGR PHB PHB2 PIAS1 PIAS2 PIAS3 PIK3R1 PIK3R3 PNRC2 POLR1B POLR2D POU2F1 POU2F2 POU4F1 POU4F2 PPARG PPARGC1A PPARGC1B PPID PRDM2 PRKACA PRMT1 PRMT2 PRPF6 PSMC5 PTEN PTGES3 PTMA PTPN1 PTPN6 RAC3 RANBP9 RARA RBBP4 RBBP7 RBFOX2 RBM23 RBM39 RELA REXO4 RFX4 RGS3 RLIM RNF14 RNF4 RPS6KA1 RPS6KA3 RXRA SAFB SAFB2 SETD7 SF1 SHC1 SKIL SKP2 SLC30A9 SMAD2 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCD1 SMARCD3 SMARCE1 SMURF1 SMYD2 SOS1 SP1 SP3 SRA1 SRC SREBF1 STAT5A STRN STUB1 SUMO1 SUV39H1 SUV420H1 SVIL TAB2 TADA3 TAF10 TAF1A TAF1B TAF2 TAP1 TBP TCF20 TDG THRA THRB TNFRSF14 TP53 TRAM1 TRIM24 TRIM25 TRIM28 TRIM59 TRIP4 TRRAP TSC2 TUBA1B TUBB UBE2I UIMC1 USF1 VAV3 WHSC1 WIPI1 XBP1 YWHAH YWHAQ ZBTB16 ZBTB17 ZNF398 176 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AKT1 ALAS1 ANGPT2 APLP1 APP ATP5B ATP6V1A ATXN3 BAD BAG6 BCCIP C1orf123 CASP3 CCDC85B CCNA1 CCNA2 CCNB1 CCNB2 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCT7 CDC42 CDC45 CDC5L CDC6 CDC7 CDK1 CDK14 CDK2 CDK3 CDK4 CDK6 CEBPA CELF3 CENPB CHGB CIZ1 CLEC3B COL4A5 COPS6 CPNE2 CPNE6 CSAD CSNK2A1 CSNK2B CTSB DAPK3 DDAH2 DEAF1 DOCK7 DYNC1I1 EEF1A1 EP300 ESR1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GADD45A GADD45B GADD45G GAPDH GCKR GDF9 GET4 GMNN GNB2 GNB2L1 GNB5 HADHB HDAC1 HDAC11 HDAC2 HDAC4 HDAC6 HERC5 HIST1H1B HMGXB3 HNRNPK HOXD8 HPD IKBKG IKZF3 ING5 INPP5K KLHL23 KMT2B KRT31 LATS2 LRIF1 MAP3K5 MAPK8 MCM10 MED31 MSH2 NGFR NKD2 NMRK2 NOV NPM1 NPRL2 NR1H2 NRBP1 OTUB1 PARP1 PCNA PDE4DIP PDHB PIM1 PKM POLD2 PSMA3 QARS RAB1A RAI1 RB1 RBBP4 RBM48 RNF126 RNF144B RPL18 RPL35 RPS2 S100A8 SDF4 SET SETDB1 SIPA1 SKP2 SLC25A11 SP110 SPRED1 STAT3 SUMO3 TAF5L TCF4 TEX11 TK1 TLE1 TMSB4X TNIP1 TNIP2 TRAF1 TRIM54 TRMT2A TSG101 TTLL5 TUBA1A TUBB2B TUBB3 TXN TXNDC11 UBC UBE2D1 UNC119 USP4 VIM VPS51 WDR73 WIZ XRCC6 YWHAQ ZBTB16 ZBTB48 ZNF135 ZNF431
Entrez ID 2099 1026
HPRD ID 00589 00298
Ensembl ID ENSG00000091831 ENSG00000124762
Uniprot IDs G4XH65 P03372 Q9UBT1 J3KQV0 P38936
PDB IDs 1A52 1AKF 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2B1Z 2B23 2BJ4 2FAI 2G44 2G5O 2I0J 2IOG 2IOK 2JF9 2JFA 2LLO 2LLQ 2OCF 2OUZ 2P15 2POG 2Q6J 2Q70 2QA6 2QA8 2QAB 2QE4 2QGT 2QGW 2QH6 2QR9 2QSE 2QXM 2QXS 2QZO 2R6W 2R6Y 2YAT 2YJA 3CBM 3CBO 3CBP 3DT3 3ERD 3ERT 3HLV 3HM1 3L03 3OS8 3OS9 3OSA 3Q95 3Q97 3UU7 3UUA 3UUC 3UUD 4AA6 4DMA 4IU7 4IUI 4IV2 4IV4 4IVW 4IVY 4IW6 4IW8 4IWC 4IWF 4JC3 4JDD 1AXC 2ZVV 2ZVW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
analyzing  brca1  carcinogenic  changed  characters  coactivator  concordant  conduct  differentiationassociated  discovered  downloaded  e2  enrichment  estradiol  go  gses9623  gsm986085  gsm986087  guidance  macs  mcf7  omnibus  ontology  p300bound  p300regulated  participated  peakcalling  software  theoretical 
antigen  arf  cd24  competitively  context  e6  glioma  hairpin  inactivation  mdm2  mutated  mutates  nearly  npm  oncogenes  overexpressed  p21  papilloma  prevents  prostate  retard  reveal  shrna  silencing  silico  somatic  sv40  tp53  viral 
Tagcloud (Difference) ?
analyzing  brca1  carcinogenic  changed  characters  coactivator  concordant  conduct  differentiationassociated  discovered  downloaded  e2  enrichment  estradiol  go  gses9623  gsm986085  gsm986087  guidance  macs  mcf7  omnibus  ontology  p300bound  p300regulated  participated  peakcalling  software  theoretical 
antigen  arf  cd24  competitively  context  e6  glioma  hairpin  inactivation  mdm2  mutated  mutates  nearly  npm  oncogenes  overexpressed  p21  papilloma  prevents  prostate  retard  reveal  shrna  silencing  silico  somatic  sv40  tp53  viral 
Tagcloud (Intersection) ?