ESR1 and RXRA

  • Number of citations of the paper that reports this interaction (PMID 9121466)
  • 34
  • Data Source:
  • BioGRID (far western blotting)
  • HPRD (in vitro)

ESR1

RXRA

Gene Name estrogen receptor 1 retinoid X receptor, alpha
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065)
  • Central corneal thickness ( 22814818 23493294)
  • Corneal structure ( 23291589)
  • Crohn's disease (need for surgery) ( 23665963)
  • Intelligence ( 22449649)
Protein-Protein Interactions 266 interactors: ACTN4 AHR AKAP13 AKT1 AKT2 AR ARHGEF15 ARNT ATAD2 BAG1 BCAR1 BCAS2 BDNF BRCA1 BTF3 CALM1 CALM2 CALM3 CAV1 CBLL1 CCNC CCND1 CCNH CCNT1 CDC25B CDK2 CDK7 CDK8 CDKN1A CEBPA CEBPB CHD9 CHUK CITED1 COPS5 CREBBP CSNK2B CTNNB1 CUEDC2 CUL4B DAP3 DDX5 DDX54 DNTTIP2 DUT EGFR EHMT2 EIF3I EP300 ERBB2 ESR2 ESRRA FHL2 FKBP4 FKBP5 FLII FOXO1 FOXO3 FOXO4 GADD45B GADD45G GNAI1 GNAI2 GNAI3 GRB2 GRIP1 GTF2B GTF2H1 HDAC4 HDAC5 HDAC9 HEXIM1 HNF4A HSP90AA1 HSP90AB1 HSPA4 HSPA8 IGF1R ING1 ISL1 ITGB3BP JUN JUNB JUND KAT5 KDM5A KIF1A KLF5 KMT2D LCK LCOR LDB1 LINC00312 LRIF1 MAPK1 MAPK14 MAPK3 MDM2 MED1 MED10 MED12 MED13 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED25 MED6 MED7 MEN1 MGMT MKNK2 MMS19 MNAT1 MPG MSH2 MTA1 MTA2 MTA3 MTCH2 MUC1 MVP NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOA7 NCOR1 NCOR2 NELFB NFKB1 NPPA NR0B1 NR0B2 NR1H4 NR2C1 NR2C2 NR2F1 NR2F6 NRIP1 NSD1 OTUB1 PAGR1 PAK1 PAK6 PELP1 PGC PGR PHB PHB2 PIAS1 PIAS2 PIAS3 PIK3R1 PIK3R3 PNRC2 POLR1B POLR2D POU2F1 POU2F2 POU4F1 POU4F2 PPARG PPARGC1A PPARGC1B PPID PRDM2 PRKACA PRMT1 PRMT2 PRPF6 PSMC5 PTEN PTGES3 PTMA PTPN1 PTPN6 RAC3 RANBP9 RARA RBBP4 RBBP7 RBFOX2 RBM23 RBM39 RELA REXO4 RFX4 RGS3 RLIM RNF14 RNF4 RPS6KA1 RPS6KA3 RXRA SAFB SAFB2 SETD7 SF1 SHC1 SKIL SKP2 SLC30A9 SMAD2 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCD1 SMARCD3 SMARCE1 SMURF1 SMYD2 SOS1 SP1 SP3 SRA1 SRC SREBF1 STAT5A STRN STUB1 SUMO1 SUV39H1 SUV420H1 SVIL TAB2 TADA3 TAF10 TAF1A TAF1B TAF2 TAP1 TBP TCF20 TDG THRA THRB TNFRSF14 TP53 TRAM1 TRIM24 TRIM25 TRIM28 TRIM59 TRIP4 TRRAP TSC2 TUBA1B TUBB UBE2I UIMC1 USF1 VAV3 WHSC1 WIPI1 XBP1 YWHAH YWHAQ ZBTB16 ZBTB17 ZNF398 113 interactors: ACVR1 ACVR1B ALOX15B ARID5A ARNTL BCL3 BRD8 CASP2 CHD9 CLOCK CNOT1 COPS2 CSNK2B CTCF CTNNB1 CTSL DNTTIP2 EDF1 ESR1 ESR2 FUS GADD45A GADD45G GATA2 GK GRIP1 GSK3B HDAC3 HDAC4 HMGA1 IGFBP3 ITGB3BP JAZF1 JMJD1C KIF1A MAPK1 MAPK3 MAPK7 MECR MED1 MED24 MED25 MPG MYOD1 NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NFKB1 NFKBIB NPAS2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR1I3 NR2E3 NR2F1 NR2F6 NR3C2 NR4A2 NRBF2 NRIP1 NSD1 PARP1 PLK1 PML POU2F1 POU2F2 PPARA PPARD PPARG PPARGC1A PRKD2 PRMT2 PSMC3IP PSMC5 RAD54L2 RARA RARB RARG RELA RNF8 ROBO4 RPS6KA6 SMAD2 SMARCD3 SMN1 SNW1 SP1 SRC SRF STAT1 TADA3 TAF11 TAF1B TBP TDG THRA THRB TK1 TMPRSS3 TRIM24 TRIP10 TRIP4 UBQLN4 VDR ZBTB16 ZNHIT3
Entrez ID 2099 6256
HPRD ID 00589 01577
Ensembl ID ENSG00000091831
Uniprot IDs G4XH65 P03372 Q9UBT1 F1D8Q5 P19793 Q6P3U7
PDB IDs 1A52 1AKF 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2B1Z 2B23 2BJ4 2FAI 2G44 2G5O 2I0J 2IOG 2IOK 2JF9 2JFA 2LLO 2LLQ 2OCF 2OUZ 2P15 2POG 2Q6J 2Q70 2QA6 2QA8 2QAB 2QE4 2QGT 2QGW 2QH6 2QR9 2QSE 2QXM 2QXS 2QZO 2R6W 2R6Y 2YAT 2YJA 3CBM 3CBO 3CBP 3DT3 3ERD 3ERT 3HLV 3HM1 3L03 3OS8 3OS9 3OSA 3Q95 3Q97 3UU7 3UUA 3UUC 3UUD 4AA6 4DMA 4IU7 4IUI 4IV2 4IV4 4IVW 4IVY 4IW6 4IW8 4IWC 4IWF 4JC3 4JDD 1BY4 1DSZ 1FBY 1FM6 1FM9 1G1U 1G5Y 1K74 1LBD 1MV9 1MVC 1MZN 1R0N 1RDT 1RXR 1XLS 1XV9 1XVP 1YNW 2ACL 2NLL 2P1T 2P1U 2P1V 2ZXZ 2ZY0 3DZU 3DZY 3E00 3E94 3FAL 3FC6 3FUG 3H0A 3KWY 3NSP 3NSQ 3OAP 3OZJ 3PCU 3R29 3R2A 3R5M 3UVV 4J5W 4J5X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
analyzing  brca1  carcinogenic  changed  characters  coactivator  concordant  conduct  differentiationassociated  discovered  downloaded  e2  enrichment  estradiol  go  gses9623  gsm986085  gsm986087  guidance  macs  mcf7  omnibus  ontology  p300bound  p300regulated  participated  peakcalling  software  theoretical 
17q  22cm  canine  centromeric  cfa9  correspond  cosmid  cryba1  distal  dog  grp78  hsa17  hsa17q  hsa9q  hsa9q34  hspa5  lies  linkage  loci  map  mmu2  nf1  occupy  painting  places  probable  syntenic  telomeric  thirds 
Tagcloud (Difference) ?
analyzing  brca1  carcinogenic  changed  characters  coactivator  concordant  conduct  differentiationassociated  discovered  downloaded  e2  enrichment  estradiol  go  gses9623  gsm986085  gsm986087  guidance  macs  mcf7  omnibus  ontology  p300bound  p300regulated  participated  peakcalling  software  theoretical 
17q  22cm  canine  centromeric  cfa9  correspond  cosmid  cryba1  distal  dog  grp78  hsa17  hsa17q  hsa9q  hsa9q34  hspa5  lies  linkage  loci  map  mmu2  nf1  occupy  painting  places  probable  syntenic  telomeric  thirds 
Tagcloud (Intersection) ?