Gene Name |
estrogen receptor 1 |
epidermal growth factor receptor |
Image |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Diethylstilbestrol
- Chlorotrianisene
- Conjugated Estrogens
- Etonogestrel
- Desogestrel
- Levonorgestrel
- Progesterone
- Raloxifene
- Toremifene
- Medroxyprogesterone
- Estrone
- Tamoxifen
- Estradiol
- Ethynodiol Diacetate
- Clomifene
- Dienestrol
- Fulvestrant
- Norgestimate
- Ethinyl Estradiol
- Melatonin
- Trilostane
- Naloxone
- Fluoxymesterone
- Estramustine
- Mestranol
- Danazol
- Allylestrenol
- Genistein
- Compound 19
- Compound 18
- Compound 4-D
- 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- Estriol
- Estropipate
- Quinestrol
- Ospemifene
- 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
- 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL
- (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
- 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
- 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
- DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
- 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
- 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL
- RALOXIFENE CORE
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Diseases |
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GWAS |
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Protein-Protein Interactions |
266 interactors:
ACTN4
AHR
AKAP13
AKT1
AKT2
AR
ARHGEF15
ARNT
ATAD2
BAG1
BCAR1
BCAS2
BDNF
BRCA1
BTF3
CALM1
CALM2
CALM3
CAV1
CBLL1
CCNC
CCND1
CCNH
CCNT1
CDC25B
CDK2
CDK7
CDK8
CDKN1A
CEBPA
CEBPB
CHD9
CHUK
CITED1
COPS5
CREBBP
CSNK2B
CTNNB1
CUEDC2
CUL4B
DAP3
DDX5
DDX54
DNTTIP2
DUT
EGFR
EHMT2
EIF3I
EP300
ERBB2
ESR2
ESRRA
FHL2
FKBP4
FKBP5
FLII
FOXO1
FOXO3
FOXO4
GADD45B
GADD45G
GNAI1
GNAI2
GNAI3
GRB2
GRIP1
GTF2B
GTF2H1
HDAC4
HDAC5
HDAC9
HEXIM1
HNF4A
HSP90AA1
HSP90AB1
HSPA4
HSPA8
IGF1R
ING1
ISL1
ITGB3BP
JUN
JUNB
JUND
KAT5
KDM5A
KIF1A
KLF5
KMT2D
LCK
LCOR
LDB1
LINC00312
LRIF1
MAPK1
MAPK14
MAPK3
MDM2
MED1
MED10
MED12
MED13
MED14
MED16
MED17
MED20
MED21
MED23
MED24
MED25
MED6
MED7
MEN1
MGMT
MKNK2
MMS19
MNAT1
MPG
MSH2
MTA1
MTA2
MTA3
MTCH2
MUC1
MVP
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOA7
NCOR1
NCOR2
NELFB
NFKB1
NPPA
NR0B1
NR0B2
NR1H4
NR2C1
NR2C2
NR2F1
NR2F6
NRIP1
NSD1
OTUB1
PAGR1
PAK1
PAK6
PELP1
PGC
PGR
PHB
PHB2
PIAS1
PIAS2
PIAS3
PIK3R1
PIK3R3
PNRC2
POLR1B
POLR2D
POU2F1
POU2F2
POU4F1
POU4F2
PPARG
PPARGC1A
PPARGC1B
PPID
PRDM2
PRKACA
PRMT1
PRMT2
PRPF6
PSMC5
PTEN
PTGES3
PTMA
PTPN1
PTPN6
RAC3
RANBP9
RARA
RBBP4
RBBP7
RBFOX2
RBM23
RBM39
RELA
REXO4
RFX4
RGS3
RLIM
RNF14
RNF4
RPS6KA1
RPS6KA3
RXRA
SAFB
SAFB2
SETD7
SF1
SHC1
SKIL
SKP2
SLC30A9
SMAD2
SMAD3
SMAD4
SMARCA2
SMARCA4
SMARCD1
SMARCD3
SMARCE1
SMURF1
SMYD2
SOS1
SP1
SP3
SRA1
SRC
SREBF1
STAT5A
STRN
STUB1
SUMO1
SUV39H1
SUV420H1
SVIL
TAB2
TADA3
TAF10
TAF1A
TAF1B
TAF2
TAP1
TBP
TCF20
TDG
THRA
THRB
TNFRSF14
TP53
TRAM1
TRIM24
TRIM25
TRIM28
TRIM59
TRIP4
TRRAP
TSC2
TUBA1B
TUBB
UBE2I
UIMC1
USF1
VAV3
WHSC1
WIPI1
XBP1
YWHAH
YWHAQ
ZBTB16
ZBTB17
ZNF398
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279 interactors:
ABL1
ABL2
ACTA1
ADRBK1
ADRM1
AGTR1
AHNAK
AHSA1
AIP
AKAP12
ALCAM
ALDOA
AMH
ANKS1A
ANKS1B
ANXA1
APBA3
APBB1
APBB2
APBB3
APPL1
AR
AREG
ARF4
ATIC
ATP1A1
ATP1B1
ATP5C1
BLK
BMX
BTC
CALM1
CALM2
CALM3
CAMK2A
CAMK2G
CAMLG
CASP1
CAV1
CAV2
CAV3
CBL
CBLB
CBLC
CBR1
CD44
CD59
CD82
CDC25A
CDH1
CEACAM1
CEBPB
CEND1
CFL1
CISH
CLNK
CLTA
CLTCL1
CMTM8
CNTN2
COL9A3
COX2
CRK
CSRP1
CTNNB1
CTNND1
DCBLD2
DCN
DCTN2
DEGS1
DNAJC4
DOK2
DOK4
DOK5
DOK6
DUSP3
DYNC1H1
EEF1G
EGF
ELF3
EPB41
EPHA2
EPPK1
EPS15
EPS8
ERBB2
ERBB3
ERBB4
EREG
ERRFI1
ESR1
EZR
FAH
FAS
FBXO25
FER
FES
FKBP4
FKBP8
FN1
GAB1
GABARAPL2
GAPDH
GNAI2
GOT1
GPM6B
GRB10
GRB14
GRB2
GRB7
HBEGF
HEXIM1
HGS
HIST3H3
HOXC10
HSP90B1
HSPA1A
HSPA4
HSPA8
HTT
ICAM1
INPPL1
IRS1
IRS4
ITGA5
JAK2
JUP
KCTD9P2
KRT17
KRT18
KRT7
KRT8
LYN
MAP2K1
MAP3K12
MAP3K14
MAP4K1
MAPK1
MAPK14
MAPK8IP1
MAPK8IP2
MAST1
MATR3
MDH1
MEGF6
MET
MGARP
MOB4
MUC1
NCAM1
NCK1
NCK2
NDN
NEDD4
NUMB
NUMBL
OAZ1
OLFM1
PAK1
PCNA
PDCD6IP
PDGFRB
PDK3
PIK3C2A
PIK3C2B
PIK3R1
PIK3R2
PIK3R3
PIN4
PITPNA
PKIA
PLCG1
PLCG2
PLD1
PLD2
PLEC
PLSCR1
PML
PPP5C
PRCC
PRDX1
PRKACA
PRKAR1A
PRKAR1B
PRKCA
PRKCB
PRKCD
PRKD1
PSMA7
PSMD4
PTGDS
PTK2
PTK2B
PTK6
PTPN1
PTPN11
PTPN12
PTPN2
PTPN6
PTPRJ
PTPRS
RAB3A
RAP1GDS1
RASA1
RGS16
RIN2
RIPK1
RNF115
RNF126
RQCD1
RUSC2
S100A7
S100A9
SCAMP1
SCAMP3
SEC13
SEPP1
SFN
SGSM2
SH2B1
SH2B3
SH2D1A
SH2D2A
SH2D3A
SH3BGRL3
SHC1
SHC2
SHC3
SLA
SLC3A2
SLC9A3R1
SMURF2
SNRPD2
SNX1
SNX2
SNX4
SNX6
SOCS1
SOCS3
SOCS4
SOCS5
SOCS7
SORBS2
SOS1
SOS2
SPARCL1
SPCS2
SRC
STAM2
STAT1
STAT3
STAT5A
STAT5B
STIP1
SYK
TGFA
TJP1
TLN1
TMCO3
TNC
TNK2
TNS4
TPI1
TPM1
TRPV1
TUBA1A
TUBA4A
UBB
UBE2V2
UCHL1
UROD
VAPA
VAV1
VAV2
VAV3
XRCC6
YWHAZ
ZAP70
ZPR1
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Entrez ID |
2099 |
1956 |
HPRD ID |
00589 |
00579 |
Ensembl ID |
ENSG00000091831
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ENSG00000146648
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Uniprot IDs |
G4XH65
P03372
Q9UBT1
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E9PFD7
P00533
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PDB IDs |
1A52
1AKF
1ERE
1ERR
1G50
1GWQ
1GWR
1HCP
1HCQ
1L2I
1PCG
1QKT
1QKU
1R5K
1SJ0
1UOM
1X7E
1X7R
1XP1
1XP6
1XP9
1XPC
1XQC
1YIM
1YIN
1ZKY
2AYR
2B1V
2B1Z
2B23
2BJ4
2FAI
2G44
2G5O
2I0J
2IOG
2IOK
2JF9
2JFA
2LLO
2LLQ
2OCF
2OUZ
2P15
2POG
2Q6J
2Q70
2QA6
2QA8
2QAB
2QE4
2QGT
2QGW
2QH6
2QR9
2QSE
2QXM
2QXS
2QZO
2R6W
2R6Y
2YAT
2YJA
3CBM
3CBO
3CBP
3DT3
3ERD
3ERT
3HLV
3HM1
3L03
3OS8
3OS9
3OSA
3Q95
3Q97
3UU7
3UUA
3UUC
3UUD
4AA6
4DMA
4IU7
4IUI
4IV2
4IV4
4IVW
4IVY
4IW6
4IW8
4IWC
4IWF
4JC3
4JDD
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1DNQ
1DNR
1IVO
1M14
1M17
1MOX
1NQL
1XKK
1YY9
1Z9I
2EB2
2EB3
2EXP
2EXQ
2GS2
2GS6
2GS7
2ITN
2ITO
2ITP
2ITQ
2ITT
2ITU
2ITV
2ITW
2ITX
2ITY
2ITZ
2J5E
2J5F
2J6M
2JIT
2JIU
2JIV
2KS1
2M20
2RF9
2RFD
2RFE
2RGP
3B2U
3B2V
3BEL
3BUO
3C09
3G5V
3G5Y
3GOP
3GT8
3IKA
3LZB
3NJP
3OB2
3OP0
3P0Y
3PFV
3POZ
3QWQ
3UG1
3UG2
3VJN
3VJO
3VRP
3VRR
3W2O
3W2P
3W2Q
3W2R
3W2S
3W32
3W33
4G5J
4G5P
4HJO
4I1Z
4I20
4I21
4I22
4I23
4I24
4JQ7
4JQ8
4JR3
4JRV
4KRL
4KRM
4KRO
4KRP
4LI5
4LL0
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
analyzing
brca1
carcinogenic
changed
characters
coactivator
concordant
conduct
differentiationassociated
discovered
downloaded
e2
enrichment
estradiol
go
gses9623
gsm986085
gsm986087
guidance
macs
mcf7
omnibus
ontology
p300bound
p300regulated
participated
peakcalling
software
theoretical
|
12q
12q21
14q31
15q25
16q23
18p
19q13
20p12
20pq
20q12
21q21
3p14
4pq
5p14
5q14
6p12
7p12
8q23
cardia
cdkn2
fist
gej
mlvi2
mts1
nrasl3
parentheses
ptpn1
rca1
xpq
xq25
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Tagcloud (Difference) ? |
analyzing
brca1
carcinogenic
changed
characters
coactivator
concordant
conduct
differentiationassociated
discovered
downloaded
e2
enrichment
estradiol
go
gses9623
gsm986085
gsm986087
guidance
macs
mcf7
omnibus
ontology
p300bound
p300regulated
participated
peakcalling
software
theoretical
|
12q
12q21
14q31
15q25
16q23
18p
19q13
20p12
20pq
20q12
21q21
3p14
4pq
5p14
5q14
6p12
7p12
8q23
cardia
cdkn2
fist
gej
mlvi2
mts1
nrasl3
parentheses
ptpn1
rca1
xpq
xq25
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Tagcloud (Intersection) ? |
|