Gene Name |
estrogen receptor 1 |
mitogen-activated protein kinase 14 |
Image |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Diethylstilbestrol
- Chlorotrianisene
- Conjugated Estrogens
- Etonogestrel
- Desogestrel
- Levonorgestrel
- Progesterone
- Raloxifene
- Toremifene
- Medroxyprogesterone
- Estrone
- Tamoxifen
- Estradiol
- Ethynodiol Diacetate
- Clomifene
- Dienestrol
- Fulvestrant
- Norgestimate
- Ethinyl Estradiol
- Melatonin
- Trilostane
- Naloxone
- Fluoxymesterone
- Estramustine
- Mestranol
- Danazol
- Allylestrenol
- Genistein
- Compound 19
- Compound 18
- Compound 4-D
- 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol
- Estriol
- Estropipate
- Quinestrol
- Ospemifene
- 17-METHYL-17-ALPHA-DIHYDROEQUILENIN
- 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL
- (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
- (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL
- 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
- dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol
- 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL
- DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE
- 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
- 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL
- RALOXIFENE CORE
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- 4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine
- N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N\'-(4-Chlorophenyl)Urea
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One
- Inhibitor of P38 Kinase
- 6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine
- 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine
- 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
- 3-(Benzyloxy)Pyridin-2-Amine
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One
- 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline
- 1-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-Urea
- 2-Chlorophenol
- 4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole
- SB220025
- 4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE
- Triazolopyridine
- 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea
- N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
- N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide
- 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one
- N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide
- 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE
- 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE
- N-cyclopropyl-2\',6-dimethyl-4\'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide
- 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
- 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde
- N-(3-cyanophenyl)-2\'-methyl-5\'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide
- N-(cyclopropylmethyl)-2\'-methyl-5\'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide
- N~3~-cyclopropyl-N~4~\'-(cyclopropylmethyl)-6-methylbiphenyl-3,4\'-dicarboxamide
- 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide
- 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
- 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol
- N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N\'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA
- N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE
- 3-FLUORO-N-1H-INDOL-5-YL-5-MORPHOLIN-4-YLBENZAMIDE
- 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE
- 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA
- 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM
- 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE
- N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide
- N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
- N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide
- 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine
- 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
- 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
- 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE
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Diseases |
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GWAS |
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Protein-Protein Interactions |
266 interactors:
ACTN4
AHR
AKAP13
AKT1
AKT2
AR
ARHGEF15
ARNT
ATAD2
BAG1
BCAR1
BCAS2
BDNF
BRCA1
BTF3
CALM1
CALM2
CALM3
CAV1
CBLL1
CCNC
CCND1
CCNH
CCNT1
CDC25B
CDK2
CDK7
CDK8
CDKN1A
CEBPA
CEBPB
CHD9
CHUK
CITED1
COPS5
CREBBP
CSNK2B
CTNNB1
CUEDC2
CUL4B
DAP3
DDX5
DDX54
DNTTIP2
DUT
EGFR
EHMT2
EIF3I
EP300
ERBB2
ESR2
ESRRA
FHL2
FKBP4
FKBP5
FLII
FOXO1
FOXO3
FOXO4
GADD45B
GADD45G
GNAI1
GNAI2
GNAI3
GRB2
GRIP1
GTF2B
GTF2H1
HDAC4
HDAC5
HDAC9
HEXIM1
HNF4A
HSP90AA1
HSP90AB1
HSPA4
HSPA8
IGF1R
ING1
ISL1
ITGB3BP
JUN
JUNB
JUND
KAT5
KDM5A
KIF1A
KLF5
KMT2D
LCK
LCOR
LDB1
LINC00312
LRIF1
MAPK1
MAPK14
MAPK3
MDM2
MED1
MED10
MED12
MED13
MED14
MED16
MED17
MED20
MED21
MED23
MED24
MED25
MED6
MED7
MEN1
MGMT
MKNK2
MMS19
MNAT1
MPG
MSH2
MTA1
MTA2
MTA3
MTCH2
MUC1
MVP
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOA7
NCOR1
NCOR2
NELFB
NFKB1
NPPA
NR0B1
NR0B2
NR1H4
NR2C1
NR2C2
NR2F1
NR2F6
NRIP1
NSD1
OTUB1
PAGR1
PAK1
PAK6
PELP1
PGC
PGR
PHB
PHB2
PIAS1
PIAS2
PIAS3
PIK3R1
PIK3R3
PNRC2
POLR1B
POLR2D
POU2F1
POU2F2
POU4F1
POU4F2
PPARG
PPARGC1A
PPARGC1B
PPID
PRDM2
PRKACA
PRMT1
PRMT2
PRPF6
PSMC5
PTEN
PTGES3
PTMA
PTPN1
PTPN6
RAC3
RANBP9
RARA
RBBP4
RBBP7
RBFOX2
RBM23
RBM39
RELA
REXO4
RFX4
RGS3
RLIM
RNF14
RNF4
RPS6KA1
RPS6KA3
RXRA
SAFB
SAFB2
SETD7
SF1
SHC1
SKIL
SKP2
SLC30A9
SMAD2
SMAD3
SMAD4
SMARCA2
SMARCA4
SMARCD1
SMARCD3
SMARCE1
SMURF1
SMYD2
SOS1
SP1
SP3
SRA1
SRC
SREBF1
STAT5A
STRN
STUB1
SUMO1
SUV39H1
SUV420H1
SVIL
TAB2
TADA3
TAF10
TAF1A
TAF1B
TAF2
TAP1
TBP
TCF20
TDG
THRA
THRB
TNFRSF14
TP53
TRAM1
TRIM24
TRIM25
TRIM28
TRIM59
TRIP4
TRRAP
TSC2
TUBA1B
TUBB
UBE2I
UIMC1
USF1
VAV3
WHSC1
WIPI1
XBP1
YWHAH
YWHAQ
ZBTB16
ZBTB17
ZNF398
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142 interactors:
AES
AIMP1
AKT1
ATF2
BAZ1B
BCL2
BICD1
BMI1
CCDC14
CCDC97
CD4
CDC25A
CDC25B
CDC25C
CDX2
CENPC
CEP164
COPS5
CREB1
CSNK2A1
CSNK2A2
CSNK2B
DDIT3
DDX26B
DUSP1
DUSP10
DUSP16
DUSP2
DUSP22
DUSP4
DUSP7
DUSP9
DYRK1B
EEA1
EEF1A1
EEF2K
EGFR
EIF4EBP1
ELK1
ELK3
ELMSAN1
EPB42
ESR1
ETV1
FKBP8
FLNA
FUBP1
GADD45A
GDF15
GMFB
GORASP2
GRB2
HDAC3
HIVEP1
HNF4A
HSF4
HTRA2
IRAK1
JDP2
JUN
JUNB
KARS
KAT2B
KMT2C
KRT18
KRT8
LIMK1
MAFA
MAP2K1
MAP2K3
MAP2K4
MAP2K6
MAP2K7
MAP3K10
MAP3K7
MAPK1
MAPK3
MAPK8
MAPKAPK2
MAPKAPK3
MAPKAPK5
MARS
MAX
MBP
MEF2A
MEF2C
MEF2D
MITF
MKNK1
MKNK2
MOB3B
MUC12
NCOA3
NFATC1
NFATC4
NKTR
NUP153
PAK6
PHC2
PI4K2B
PLA2G4A
PLG
PML
PPARGC1A
PTPN7
RBSN
RELA
RET
ROBO1
RPL22
RPL41
RPS6KA4
RPS6KA5
SCN8A
SH2D1A
SHC1
SLC9A1
SMAD3
SMAD7
SMARCD3
SMEK1
SNAPIN
SPAG9
SPTBN1
SQSTM1
SRPK1
SRSF5
STAT1
STAT4
STK39
SUPT20H
TAB1
TCF20
TFCP2
TMEM63B
TP53
TRAF6
UGT2B10
YY1AP1
ZFP36L1
ZNF142
ZNHIT1
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Entrez ID |
2099 |
1432 |
HPRD ID |
00589 |
02619 |
Ensembl ID |
ENSG00000091831
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ENSG00000112062
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Uniprot IDs |
G4XH65
P03372
Q9UBT1
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L7RSM2
Q16539
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PDB IDs |
1A52
1AKF
1ERE
1ERR
1G50
1GWQ
1GWR
1HCP
1HCQ
1L2I
1PCG
1QKT
1QKU
1R5K
1SJ0
1UOM
1X7E
1X7R
1XP1
1XP6
1XP9
1XPC
1XQC
1YIM
1YIN
1ZKY
2AYR
2B1V
2B1Z
2B23
2BJ4
2FAI
2G44
2G5O
2I0J
2IOG
2IOK
2JF9
2JFA
2LLO
2LLQ
2OCF
2OUZ
2P15
2POG
2Q6J
2Q70
2QA6
2QA8
2QAB
2QE4
2QGT
2QGW
2QH6
2QR9
2QSE
2QXM
2QXS
2QZO
2R6W
2R6Y
2YAT
2YJA
3CBM
3CBO
3CBP
3DT3
3ERD
3ERT
3HLV
3HM1
3L03
3OS8
3OS9
3OSA
3Q95
3Q97
3UU7
3UUA
3UUC
3UUD
4AA6
4DMA
4IU7
4IUI
4IV2
4IV4
4IVW
4IVY
4IW6
4IW8
4IWC
4IWF
4JC3
4JDD
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1A9U
1BL6
1BL7
1BMK
1DI9
1IAN
1KV1
1KV2
1M7Q
1OUK
1OUY
1OVE
1OZ1
1R39
1R3C
1W7H
1W82
1W83
1W84
1WBN
1WBO
1WBS
1WBT
1WBV
1WBW
1WFC
1YQJ
1ZYJ
1ZZ2
1ZZL
2BAJ
2BAK
2BAL
2BAQ
2FSL
2FSM
2FSO
2FST
2GFS
2I0H
2LGC
2NPQ
2OKR
2ONL
2QD9
2RG5
2RG6
2Y8O
2YIS
2YIW
2YIX
2ZAZ
2ZB0
2ZB1
3BV2
3BV3
3BX5
3C5U
3CTQ
3D7Z
3D83
3DS6
3DT1
3E92
3E93
3FC1
3FI4
3FKL
3FKN
3FKO
3FL4
3FLN
3FLQ
3FLS
3FLW
3FLY
3FLZ
3FMH
3FMJ
3FMK
3FML
3FMM
3FMN
3FSF
3FSK
3GC7
3GCP
3GCQ
3GCS
3GCU
3GCV
3GFE
3GI3
3HA8
3HEC
3HEG
3HL7
3HLL
3HP2
3HP5
3HRB
3HUB
3HUC
3HV3
3HV4
3HV5
3HV6
3HV7
3HVC
3IPH
3ITZ
3IW5
3IW6
3IW7
3IW8
3K3I
3K3J
3KF7
3KQ7
3L8S
3L8X
3LFA
3LFB
3LFC
3LFD
3LFE
3LFF
3LHJ
3MGY
3MH0
3MH1
3MH2
3MH3
3MPA
3MPT
3MVL
3MVM
3MW1
3NEW
3NNU
3NNV
3NNW
3NNX
3NWW
3O8P
3O8T
3O8U
3OBG
3OBJ
3OC1
3OCG
3OD6
3ODY
3ODZ
3OEF
3PG3
3QUD
3QUE
3RIN
3ROC
3S3I
3S4Q
3U8W
3UVP
3UVQ
3UVR
3ZS5
3ZSG
3ZSH
3ZSI
3ZYA
4A9Y
4AA0
4AA4
4AA5
4AAC
4DLI
4DLJ
4E5A
4E5B
4E6A
4E6C
4E8A
4EH2
4EH3
4EH4
4EH5
4EH6
4EH7
4EH8
4EH9
4EHV
4EWQ
4F9W
4F9Y
4FA2
4GEO
4KIN
4KIP
4KIQ
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Enriched GO Terms of Interacting Partners? |
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|
Tagcloud ? |
analyzing
brca1
carcinogenic
changed
characters
coactivator
concordant
conduct
differentiationassociated
discovered
downloaded
e2
enrichment
estradiol
go
gses9623
gsm986085
gsm986087
guidance
macs
mcf7
omnibus
ontology
p300bound
p300regulated
participated
peakcalling
software
theoretical
|
acta2
cdh1
cdkn1a
cldn1
cldn4
cldn7
ctnnb1
fn1
krt19
mapk3
mki67
mmp2
mmp9
muc5ac
muc6
nes
pdac
pdacs
ptgs2
rps6
rps6kb1
smad4
stains
surprising
synchronous
tgfb1
tgfbr1
vim
|
Tagcloud (Difference) ? |
analyzing
brca1
carcinogenic
changed
characters
coactivator
concordant
conduct
differentiationassociated
discovered
downloaded
e2
enrichment
estradiol
go
gses9623
gsm986085
gsm986087
guidance
macs
mcf7
omnibus
ontology
p300bound
p300regulated
participated
peakcalling
software
theoretical
|
acta2
cdh1
cdkn1a
cldn1
cldn4
cldn7
ctnnb1
fn1
krt19
mapk3
mki67
mmp2
mmp9
muc5ac
muc6
nes
pdac
pdacs
ptgs2
rps6
rps6kb1
smad4
stains
surprising
synchronous
tgfb1
tgfbr1
vim
|
Tagcloud (Intersection) ? |
|